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Rational Design and Development of Novel CDK9 Inhibitors for the Treatment of Acute Myeloid Leukemia 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64, 期号: 19, 页码: 14647-14663
作者:  Han, Xu;  Song, Ning;  Saidahmatov, Abdusaid;  Wang, Peipei;  Wang, Yong
Adobe PDF(5151Kb)  |  收藏  |  浏览/下载：526/0  |  提交时间：2021/11/19
Discovery of thalidomide-based PROTAC small molecules as the highly efficient SHP2 degraders 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 218
作者:  Yang, Xiangbo;  Wang, Zhijia;  Pei, Yuan;  Song, Ning;  Xu, Lei
Adobe PDF(1954Kb)  |  收藏  |  浏览/下载：306/0  |  提交时间：2021/06/04
Discovery of (R)-5-((5-(1-methyl-1H-pyrazol-4-yl)-4-(methylamino) pyrimidin-2-yl)amino)-3-(piperidin-3-yloxy)picolinonitrile, a novel CHK1 inhibitor for hematologic malignancies 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 173, 页码: 44-62
作者:  Tong, Lexian;  Song, Pinrao;  Jiang, Kailong;  Xu, Lei;  Jin, Tingting
Adobe PDF(1046Kb)  |  收藏  |  浏览/下载：610/12  |  提交时间：2019/06/04
Development of Macrocyclic Peptides Containing Epoxyketone with Oral Availability as Proteasome Inhibitors 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 61, 期号: 20, 页码: 9177-9204
作者:  Li, Daqiang;  Zhang, Xiaotuan;  Ma, Xiaodong;  Xu, Lei;  Yu, Jianjun
Adobe PDF(4610Kb)  |  收藏  |  浏览/下载：644/0  |  提交时间：2018/11/15
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