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Efficient Production of 9,22-Dihydroxy-23,24-bisnorchol-4-ene-3-one from Phytosterols by Modifying Multiple Genes in
Mycobacterium fortuitum
期刊论文
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2024, 卷号: 25, 期号: 7
作者:
Han, Suwan
;
Liu, Xiangcen
;
He, Beiru
;
Zhai, Xinghui
;
Yuan, Chenyang
Adobe PDF(1516Kb)
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收藏
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浏览/下载:158/0
|
提交时间:2024/05/14
C22 steroids
9,22-dihydroxy-23,24-bisnorchol-4-enehp-3-one(9-OHBA)
Mycobacterium fortuitum
phytosterol
hsd4A
fadA5
Phytosterol conversion into C9 non-hydroxylated derivatives through gene regulation in
Mycobacterium fortuitum
期刊论文
APPLIED MICROBIOLOGY AND BIOTECHNOLOGY, 2023
作者:
Liu, Xiangcen
;
He, Beiru
;
Zhang, Jingxian
;
Yuan, Chenyang
;
Han, Suwan
Adobe PDF(1340Kb)
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收藏
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浏览/下载:333/0
|
提交时间:2023/11/13
Androst-4-ene-3,17-dione
3-ketosteroid-9 alpha-hydroxylase
22-hydroxy-23,24-bisnorchol-4-ene-3-one
Mycobacterium fortuitum
Phytosterol
Functional analysis of acyl-CoA dehydrogenases and their application to C22 steroid production
期刊论文
APPLIED MICROBIOLOGY AND BIOTECHNOLOGY, 2023, 卷号: 107, 期号: 11, 页码: 3419-3428
作者:
Yuan, Chenyang
;
Li, Yixin
;
Han, Suwan
;
He, Beiru
;
Zhai, Xinghui
Adobe PDF(2669Kb)
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收藏
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浏览/下载:423/0
|
提交时间:2023/04/18
Acyl-CoA dehydrogenase
ChsE
3-oxo-4,17-pregadiene-20-carboxylic acid methyl ester
steroids side-chain degradation
Improving the production of 9 alpha-hydroxy-4-androstene-3,17-dione from phytosterols by 3-ketosteroid-Delta(1)-dehydrogenase deletions and multiple genetic modifications in Mycobacterium fortuitum
期刊论文
MICROBIAL CELL FACTORIES, 2023, 卷号: 22, 期号: 1
作者:
Liu, Xiangcen
;
Zhang, Jingxian
;
Yuan, Chenyang
;
Du, Guilin
;
Han, Suwan
Adobe PDF(1604Kb)
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收藏
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浏览/下载:769/245
|
提交时间:2023/04/10
9 alpha-hydroxy-4-androstene-3
17-dione
Phytosterol
3-ketosteroid- increment (1)-dehydrogenase
Mycobacterium fortuitum
Production of 21-hydroxy-20-methyl-pregna-1,4-dien-3-one by modifying multiple genes in Mycolicibacterium
期刊论文
APPLIED MICROBIOLOGY AND BIOTECHNOLOGY, 2023, 卷号: 107, 期号: 5-6, 页码: 1563-1574
作者:
Yuan, Chenyang
;
Ma, Zhiguo
;
Li, Yixin
;
Zhang, Jingxian
Adobe PDF(3183Kb)
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收藏
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浏览/下载:273/1
|
提交时间:2023/03/10
Alcohols
Lipids
21-hydroxy-20-methyl-pregnum-1,4-dien-3-one
C22 steroid
Drug synthesis
Hydroxylases
Multiple genes
Mycolicibacteria
NADH oxidase
Phytosterol
Prednisolone
Steroids drugs
Phytosterol conversion into C9 non-hydroxylated derivatives through gene regulation in Mycobacterium fortuitum
期刊论文
APPLIED MICROBIOLOGY AND BIOTECHNOLOGY, 2023, 卷号: 107, 期号: 24, 页码: 7635-7646
作者:
Liu, Xiangcen
;
He, Beiru
;
Zhang, Jingxian
;
Yuan, Chenyang
;
Han, Suwan
Adobe PDF(1340Kb)
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收藏
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浏览/下载:321/0
|
提交时间:2023/10/27
Alcohols
Genes
Metabolic engineering
22-hydroxy-23,24-bisnorchol-4-ene-3-one
3-ketosteroid-9α-hydroxylase
Androst-4-ene-3,17-dione
Dual function
Gene-regulation
Hydroxylases
Hydroxysteroid dehydrogenase
Mycobacteria fortuitum
Phytosterol
Thioesterases
Optimized strategy valorizing unautoclaved cottonseed hull as ruminant alternative feeds via solid-state fermentation: Detoxifying polyphenols, restraining hazardous microflora and antibiotic-resistance gene hosts
期刊论文
ENVIRONMENTAL TECHNOLOGY AND INNOVATION, 2022, 卷号: 28
作者:
Du, Guilin
;
Zhou, Yan
;
Zhang, Jingxian
;
Han, Suwan
;
Liu, Xiangcen
Adobe PDF(2654Kb)
|
收藏
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浏览/下载:324/1
|
提交时间:2022/12/16
Amino acids
Antioxidants
Biodegradability
Biodegradation
Developing countries
Energy utilization
Enzymes
Fermentation
Flavonoids
Genes
Oilseeds
Physicochemical properties
Tannins
Agro-industrial byproducts
Condensed tannins
Free gossypol
Functional gene set
Functional genes
Gene sets
Polyphenols
Solid-state fermentation
Waste valorizations
White rot fungi
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