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Recent advances in targeted degradation in the RAS pathway 期刊论文
FUTURE MEDICINAL CHEMISTRY, 2025, 卷号: 17, 期号: 6
作者:  Ge, Zhiming;  Fan, Zisheng;  He, Wei;  Zhou, Guizhen;  Zhou, Yidi
Adobe PDF(2827Kb)  |  收藏  |  浏览/下载：25/2  |  提交时间：2025/03/25
Ginkgetin Alleviates Inflammation and Senescence by Targeting STING 期刊论文
ADVANCED SCIENCE, 2024, 卷号: 12, 期号: 2
作者:  Yadan Liu;  Jialin Ye;  Zisheng Fan;  Xiaolong Wu;  Yinghui Zhang
Adobe PDF(5894Kb)  |  收藏  |  浏览/下载：237/19  |  提交时间：2024/11/27
Targeting STING oligomerization with licochalcone D ameliorates STING-driven inflammatory diseases 期刊论文
SCIENCE CHINA-LIFE SCIENCES, 2024
作者:  Zhang, Yinghui;  Liu, Yadan;  Jiang, Bing;  Chen, Lifan;  Hu, Jie
Adobe PDF(4423Kb)  |  收藏  |  浏览/下载：275/5  |  提交时间：2024/09/08
Design, Synthesis, and Biological Evaluation of Potent and Selective PROTAC Degraders of Oncogenic KRASG12D 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 67, 期号: 2
作者:  Zhou, Chuan;  Fan, Zisheng;  Gu, Yuejiao;  Ge, Zhiming;  Tao, Zhaofan
Adobe PDF(8664Kb)  |  收藏  |  浏览/下载：308/14  |  提交时间：2024/03/04
Synthesis and Biological Evaluation of β‐Lactam Derivatives Targeting Speckle-Type POZ Protein (SPOP) 期刊论文
ACS MEDICINAL CHEMISTRY LETTERS, 2024
作者:  Chenmao Zhou;  Xinyue Hao;  Zhengyang Chen;  Runze Zhang;  Qian Zhou
Adobe PDF(3478Kb)  |  收藏  |  浏览/下载：127/0  |  提交时间：2024/11/27
Sequence-based drug design as a concept in computational drug design 期刊论文
NATURE COMMUNICATIONS, 2023, 卷号: 14, 期号: 1
作者:  Chen, Lifan;  Fan, Zisheng;  Chang, Jie;  Yang, Ruirui;  Hou, Hui
Adobe PDF(3338Kb)  |  收藏  |  浏览/下载：545/181  |  提交时间：2023/08/21
Discovery of ARF1-targeting inhibitor demethylzeylasteral as a potential agent against breast cancer 期刊论文
ACTA PHARMACEUTICA SINICA B, 2022, 卷号: 12, 期号: 5
作者:  Chang, Jie;  Yang, Ruirui;  Chen, Lifan;  Fan, Zisheng;  Zhou, Jingyi
Adobe PDF(875Kb)  |  收藏  |  浏览/下载：217/0  |  提交时间：2022/07/01
Drug target inference by mining transcriptional data using a novel graph convolutional network framework 期刊论文
PROTEIN & CELL, 2022
作者:  Zhong, Feisheng;  Wu, Xiaolong;  Yang, Ruirui;  Li, Xutong;  Wang, Dingyan
Adobe PDF(3167Kb)  |  收藏  |  浏览/下载：446/0  |  提交时间：2021/11/05
Active Learning for Drug Design: A Case Study on the Plasma Exposure of Orally Administered Drugs 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64, 期号: 22
作者:  Ding, Xiaoyu;  Cui, Rongrong;  Yu, Jie;  Liu, Tiantian;  Zhu, Tingfei
Adobe PDF(4647Kb)  |  收藏  |  浏览/下载：378/0  |  提交时间：2022/02/28
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