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Photochemically controlled activation of STING by CAIX-targeting photocaged agonists to suppress tumor cell growth 期刊论文
CHEMICAL SCIENCE, 2023, 卷号: 14, 期号: 22, 页码: 5956-5964
作者:  Ding, Chunyong;  Du, Mengyan;  Xiong, Zhi;  Wang, Xue;  Li, Hongji
Adobe PDF(1667Kb)  |  收藏  |  浏览/下载：323/1  |  提交时间：2023/06/02
Structure-Activity relationship study of benzothiophene oxobutanoic acid analogues leading to novel stimulator of interferon gene (STING) agonists 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 241
作者:  Shen, Ancheng;  Li, Xiyuan;  Zhang, Yan;  Ma, Jing;  Xiao, Ruoxuan
Adobe PDF(6740Kb)  |  收藏  |  浏览/下载：425/0  |  提交时间：2023/01/16
Synthesis and pharmacological validation of fluorescent diarylsulfonylurea analogues as NLRP3 inhibitors and imaging probes 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 237
作者:  Zhao, Jiannan;  Li, Yongling;  Ma, Jing;  Liu, Jingting;  Xiao, Ruoxuan
Adobe PDF(2509Kb)  |  收藏  |  浏览/下载：338/0  |  提交时间：2022/05/05
Synthesis and Pharmacological Evaluation of Tetrahydro-gamma-carboline Derivatives as Potent Anti-inflammatory Agents Targeting Cyclic GMP-AMP Synthase 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64, 期号: 11, 页码: 7667-7690
作者:  Tan, Jing;  Wu, Bing;  Chen, Tingting;  Fan, Chen;  Zhao, Jiannan
Adobe PDF(5732Kb)  |  收藏  |  浏览/下载：322/0  |  提交时间：2021/07/09
Development of hedgehog pathway inhibitors by epigenetically targeting GLI through BET bromodomain for the treatment of medulloblastoma 期刊论文
ACTA PHARMACEUTICA SINICA B, 2021, 卷号: 11, 期号: 2, 页码: 488-504
作者:  Liu, Xiaohua;  Zhang, Yu;  Li, Yalei
Adobe PDF(3481Kb)  |  收藏  |  浏览/下载：424/0  |  提交时间：2021/04/01
Design, synthesis and antitumor study of a series of N-Cyclic sulfamoylaminoethyl substituted 1,2,5-oxadiazol-3-amines as new indoleamine 2, 3-dioxygenase 1 (IDO1) inhibitors 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 179, 页码: 38-55
作者:  Chen, Shulun;  Guo, Wei;  Liu, Xiaohua;  Sun, Pu;  Wang, Yi
Adobe PDF(2633Kb)  |  收藏  |  浏览/下载：310/11  |  提交时间：2019/10/14
Discovery of Indoleamine 2,3-Dioxygenase 1 (IDO-1) Inhibitors Based on Ortho-Naphthaquinone-Containing Natural Product 期刊论文
MOLECULES, 2019, 卷号: 24, 期号: 6
作者:  Zhao, Hongchuan;  Sun, Pu;  Guo, Wei;  Wang, Yi;  Zhang, Ao
Adobe PDF(6921Kb)  |  收藏  |  浏览/下载：1076/297  |  提交时间：2019/05/08
Total synthesis of (+/-)-tanshinol B, tanshinone I, and (+/-)-tanshindiol B, and C 期刊论文
ORGANIC & BIOMOLECULAR CHEMISTRY, 2018, 卷号: 16, 期号: 18, 页码: 3376-3381
作者:  Wang, Fan;  Yang, Hong;  Yu, Shujuan;  Xue, Yu;  Fan, Zhoulong
Adobe PDF(817Kb)  |  收藏  |  浏览/下载：563/0  |  提交时间：2018/06/13
Structural Modification of Natural Product Tanshinone I Leading to Discovery of Novel Nitrogen-Enriched Derivatives with Enhanced Anticancer Profile and Improved Drug-like Properties 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 61, 期号: 3, 页码: 760-776
作者:  Ding, Chunyong;  Tian, Qianting;  Li, Jie;  Jiao, Mingkun;  Song, Shanshan
Adobe PDF(2934Kb)  |  收藏  |  浏览/下载：482/1  |  提交时间：2018/03/01
Difluorination of Furonaphthoquinones 期刊论文
JOURNAL OF ORGANIC CHEMISTRY, 2017, 卷号: 82, 期号: 14, 页码: 7388-7393
作者:  Li, Jie;  Xue, Yu;  Fan, Zhoulong;  Ding, Chunyong;  Zhang, Ao
Adobe PDF(1040Kb)  |  收藏  |  浏览/下载：397/0  |  提交时间：2017/08/26
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