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Structural insights into the high basal activity and inverse agonism of the orphan receptor GPR6 implicated in Parkinson's disease 期刊论文
SCIENCE SIGNALING, 2024, 卷号: 17, 期号: 865
作者:  Barekatain, Mahta;  Johansson, Linda C.;  Lam, Jordy H.;  Chang, Hao;  Sadybekov, Anastasiia V.
Adobe PDF(1755Kb)  |  收藏  |  浏览/下载:306/12  |  提交时间:2024/12/17
Structure basis of ligand recognition and activation of GPR55 期刊论文
CELL RESEARCH, 2024
作者:  Chang, Hao;  Li, Xiaoting;  Shen, Ling;  Ge, Xuanrui;  Hao, Shuming
Adobe PDF(1392Kb)  |  收藏  |  浏览/下载:376/21  |  提交时间:2024/11/11
The activation mechanism and antibody binding mode for orphan GPR20 期刊论文
CELL DISCOVERY;, 2023, 卷号: 9, 期号: 1
作者:  Lin, Xi;  Jiang, Shan;  Wu, Yiran;  Wei, Xiaohu;  Han, Gye-Won
Adobe PDF(3056Kb)  |  收藏  |  浏览/下载:1238/272  |  提交时间:2023/03/24
Elucidating the active delta-opioid receptor crystal structure with peptide and small-molecule agonists 期刊论文
SCIENCE ADVANCES, 2019, 卷号: 5, 期号: 11
作者:  Claff, Tobias;  Yu, Jing;  Blais, Veronique;  Patel, Nilkanth;  Martin, Charlotte
Adobe PDF(1244Kb)  |  收藏  |  浏览/下载:2703/1378  |  提交时间:2019/12/19
Crystal structure of misoprostol bound to the labor inducer prostaglandin E-2 receptor 期刊论文
NATURE CHEMICAL BIOLOGY, 2019, 卷号: 15, 期号: 1, 页码: 11-+
作者:  Audet, Martin;  White, Kate L.;  Breton, Billy;  Zarzycka, Barbara;  Han, Gye Won
Adobe PDF(2500Kb)  |  收藏  |  浏览/下载:755/2  |  提交时间:2019/01/05
Computational design of thermostabilizing point mutations for G protein-coupled receptors 期刊论文
ELIFE, 2018, 卷号: 7
作者:  Popov, Petr;  Peng, Yao;  Shen, Ling;  Stevens, Raymond C.;  Cherezov, Vadim
Adobe PDF(2235Kb)  |  收藏  |  浏览/下载:1035/4  |  提交时间:2018/08/09
Identification of Phosphorylation Codes for Arrestin Recruitment by G Protein-Coupled Receptors 期刊论文
CELL, 2017, 卷号: 170, 期号: 3, 页码: 457-+
作者:  Zhou, X. Edward;  He, Yuanzheng;  de Waal, Parker W.;  Gao, Xiang;  Kang, Yanyong
Adobe PDF(8411Kb)  |  收藏  |  浏览/下载:743/1  |  提交时间:2017/08/26
Crystal structure of a multi-domain human smoothened receptor in complex with a super stabilizing ligand 期刊论文
NATURE COMMUNICATIONS, 2017, 卷号: 8, 期号: 1
作者:  Zhang, Xianjun;  Zhao, Fei;  Wu, Yiran;  Yang, Jun;  Han, Gye Won
Adobe PDF(1662Kb)  |  收藏  |  浏览/下载:1684/420  |  提交时间:2017/07/04
Native phasing of x-ray free-electron laser data for a G protein-coupled receptor 期刊论文
SCIENCE ADVANCES, 2016, 卷号: 2, 期号: 9
作者:  Batyuk, Alexander;  Galli, Lorenzo;  Ishchenko, Andrii;  Han, Gye Won;  Gati, Cornelius
Adobe PDF(1685Kb)  |  收藏  |  浏览/下载:1693/319  |  提交时间:2017/11/02
Serial femto-second crystallography datasets from G protein-coupled receptors 期刊论文
SCIENTIFIC DATA, 2016, 卷号: 3
作者:  White, Thomas A.;  Barty, Anton;  Liu, Wei;  Ishchenko, Andrii;  Zhang, Haitao
Adobe PDF(1089Kb)  |  收藏  |  浏览/下载:1265/315  |  提交时间:2017/07/04
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