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Discovery of CZL-046 with an (S)-3-Fluoropyrrolidin-2-one Scaffold as a p300 Bromodomain Inhibitor for the Treatment of Multiple Myeloma 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 67, 期号: 20
作者:  Chen, Zonglong;  Yang, Hong;  Zhang, Yan;  Lyu, Xiaodong;  Shi, Qiongyu
Adobe PDF(5876Kb)  |  收藏  |  浏览/下载:134/1  |  提交时间:2024/10/14
Design, synthesis and biological evaluation of (R)-5-methylpyrrolidin-2-ones as p300 bromodomain inhibitors with Anti-Tumor activities in multiple tumor lines 期刊论文
BIOORGANIC CHEMISTRY, 2022, 卷号: 124
作者:  Liu, Ruiqi;  Yang, Hong;  Chen, Zonglong;  Zhou, Kaixin;  Shi, Qiongyu
Adobe PDF(2004Kb)  |  收藏  |  浏览/下载:178/0  |  提交时间:2022/05/05
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