消息
×
loading..
中文版 | English

在结果中检索

KMS

浏览/检索结果: 共137条，第1-10条 帮助

已选(0)清除 条数/页：   排序方式：
Discovery of novel and highly potent anticancer agents enabled by selenium scanning of noscapine 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 293
作者:  Li, Defeng;  Shen, Shuting;  Liu, Chuanxu;  Guo, Tingyu;  Liu, Yuhuan
Adobe PDF(19864Kb)  |  收藏  |  浏览/下载：15/3  |  提交时间：2025/05/26
Structural Optimization of Next-generation TRK Inhibitors against Acquired Drug Resistance Mutations for the Treatment of Solid Tumors 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2025
作者:  Zichao Xu（许子超）;  Yueling Liu
收藏  |  浏览/下载：28/0  |  提交时间：2025/05/20
Conformational restriction enables discovering a series of chroman derivatives as potent and selective Nav1.8 inhibitors with improved pharmacokinetic properties 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 293, 页码: 117697
作者:  Li N(李娜);  Wang LL(王琳琳);  Hu XY(胡新园);  Xu HY(许海燕);  Yang BW(杨博文)
Adobe PDF(4737Kb)  |  收藏  |  浏览/下载：11/3  |  提交时间：2025/05/20
Structure-activity relationship analysis of meta-substituted N-cyclopropylmethyl-nornepenthones with mixed KOR/MOR activities 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 289
作者:  Tang, Siyuan;  Hu, Shuyang;  Feng, Lijing;  Kong, Linghui;  Gui, Jiangwen
Adobe PDF(2887Kb)  |  收藏  |  浏览/下载：46/1  |  提交时间：2025/03/25
D-morphinan analogs with favorable pharmacokinetic profiles as dual-acting antidepressants (vol 287, 117349, 2025) 其他
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2025-05-05, 卷号: 289
作者:  Ji, Jing;  Hu, Zhengtao;  Zheng, Fuqiang;  Zheng, Jiefang;  Cheng, Jiaxin
收藏  |  浏览/下载：32/0  |  提交时间：2025/04/14
Expanding the utilization of binding pockets proves to be effective for noncovalent small molecule inhibitors against SARS-CoV-2 Mpro 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 289
作者:  Yang, Qi;  Huang, Xupeng;  Zhang, Hongbo;  Sun, Jing;  Tang, Jielin
Adobe PDF(5890Kb)  |  收藏  |  浏览/下载：95/9  |  提交时间：2025/04/07
Discovery of Highly Potent and Selective EZH2 Covalent Inhibitors via Incorporating Basic Amines 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2025
作者:  Zhang, Yi;  Shi, Qiongyu;  Fang, Wei;  Liu, Li;  Yang, Hong
Adobe PDF(4720Kb)  |  收藏  |  浏览/下载：7/1  |  提交时间：2025/05/20
Identification of a RANKL/TNF-α Dual-Inhibitor as a Potential Disease-Modifying Agent for the Treatment of Knee Osteoarthritis 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2025
作者:  Shao, Zhengguang;  Wang, Tianqi;  Yan, Xueming;  Ning, Ruonan;  Xu, Xing
Adobe PDF(8900Kb)  |  收藏  |  浏览/下载：16/2  |  提交时间：2025/05/16
Discovery of 3‑(Fluoro-imidazolyl)pyridazine Derivatives as Potent STING Agonists with Antitumor Activity 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2025
作者:  Hou, Hui;  Zhou, Jingyi;  Sui, Qibang;  Zhang, Changfa;  Su, Zhaoming
Adobe PDF(9996Kb)  |  收藏  |  浏览/下载：21/5  |  提交时间：2025/05/15
Heterocycle-fused phenylcyclohexylamines as novel multi-target antagonists of N-methyl-D-aspartate (NMDA) receptor and monoamine transporter for treating depression 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 291
作者:  Zheng, Fuqiang;  Hu, Zhengtao;  Chen, Hai;  Cheng, Jiaxin;  Hou, Qiongqiong
Adobe PDF(10409Kb)  |  收藏  |  浏览/下载：91/21  |  提交时间：2025/04/10
  • 首页
  • 上一页
  • 1
  • 2
  • 3
  • 4
  • 5
  • 6
  • 7
  • 8
  • 9
  • 下一页
  • 末页