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成果统计

合作作者[TOP 5]

  • Ling, Zhiyang

    合作成果数：13

  • Zhang, Yaguang

    合作成果数：12

  • Yi, Chunyan

    合作成果数：11

  • Ma, Liyan

    合作成果数：10

  • Sun, Xiaoyu

    合作成果数：10
孙兵 中科院特聘教授
所在学院： 生命科学与技术学院
职务： 巴斯德所联合所长
研究方向： 分子免疫、分子病毒（中科院上海巴斯德研究所研究员）
备注： --
孙兵

研究内容

树突状细胞(DC)在先天性免疫应答,免疫识别和活化T细胞中发挥有重要的作用。幼稚性T细胞分可以化成不同的效应性T细胞，进而诱导获得性免疫应答，调节细胞免疫和体液免疫。Th细胞在诱发多种器官特异性自身免疫病、器官移植排斥反应和哮喘疾病中发挥有核心作用。本实验室重点研究DC的成熟与分化，以及CD4+辅助性T细胞的分化机制和功能，寻找并鉴定一系列调控DC和Th细胞功能的新分子。通过研究这些重要分子的功能，为防治人类器官特异性自身免疫病和过敏性哮喘疾病，提供新的研究思路和防治策略。

科研成果

23 15603 3801 1260 0 15
Items Views Downloads TC[WOS] TC[CSCD] H-index
排序方式：
 [1] Wang, Su.,Zhong, Shufen.,Huang, Ying.,Zhu, Songling.,Chen, Shuangfeng.,...&Sun, Bing.(2024).MDM2 Is Essential to Maintain the Homeostasis of Epithelial Cells by Targeting p53.JOURNAL OF INNATE IMMUNITY,16(1).浏览/下载:173/1; 被引[WOS]:1; IF:4.7/5.7评论推荐收藏
 [2] Liu, Lian.,Zhang, Danyan.,Fan, Rong.,Cheng, Shipeng.,Yang, Jichao.,...&Niu, Junqi.(2024).Serum ECM1 is a promising biomarker for staging and monitoring fibrosis in patients with chronic hepatitis B.SCIENCE CHINA-LIFE SCIENCES.浏览/下载:241/5; 被引[WOS]:0; IF:8.0/7.3评论推荐收藏
 [3] Sun, Xiaoyu.,Ma, Hanwen.,Wang, Xuanjia.,Bao, Zhiheng.,Tang, Shubing.,...&Sun, Bing.(2024).Broadly neutralizing antibodies to combat influenza virus infection.ANTIVIRAL RESEARCH,221.浏览/下载:280/0; 被引[WOS]:9; IF:4.5/5.0评论推荐收藏
 [4] Sun, Bing,Xia, Ningshao,&Zhang, Xuan.(2023).Progress in immunotherapy.SCIENCE CHINA-LIFE SCIENCES.浏览/下载:714/226; 被引[WOS]:7; IF:8.0/7.3评论推荐收藏
 [5] Yi, Chunyan.,Su, Caixia.,Sun, Xiaoyu.,Lu, Xiao.,Si, Chuanya.,...&Sun, Bing.(2023).A human antibody potently neutralizes RSV by targeting the conserved hydrophobic region of prefusion F.SCIENCE CHINA LIFE SCIENCES;.浏览/下载:622/195; 被引[WOS]:2; IF:8.0/7.3评论推荐收藏
 [6] Ling, Zhiyang,Yi, Chunyan,Sun, Xiaoyu,Yang, Zhuo,&Sun, Bing.(2022).Broad strategies for neutralizing SARS-CoV-2 and other human coronaviruses with monoclonal antibodies.SCIENCE CHINA-LIFE SCIENCES.浏览/下载:697/238; 被引[WOS]:8; IF:8.0/7.3评论推荐收藏
 [7] Chen, Wen.,Chen, Shuangfeng.,Yan, Chenghua.,Zhang, Yaguang.,Zhang, Ronghua.,...&Sun, Bing.(2022).Allergen protease-activated stress granule assembly and gasdermin D fragmentation control interleukin-33 secretion.NATURE IMMUNOLOGY.浏览/下载:1154/363; 被引[WOS]:65; IF:27.7/28.3评论推荐收藏
 [8] Sun, Xiaoyu.,Yi, Chunyan.,Zhu, Yuanfei.,Ding, Longfei.,Xia, Shuai.,...&Sun, Bing.(2022).Neutralization mechanism of a human antibody with pan-coronavirus reactivity including SARS-CoV-2.NATURE MICROBIOLOGY,7(7).浏览/下载:1362/450; 被引[WOS]:81; IF:20.5/21.0评论推荐收藏
 [9] Yi, Chunyan,Sun, Xiaoyu,Ling, Zhiyang,&Sun, Bing.(2022).Jigsaw puzzle of SARS-CoV-2 RBD evolution and immune escape.CELLULAR & MOLECULAR IMMUNOLOGY.浏览/下载:601/221; 被引[WOS]:7; IF:21.8/19.9评论推荐收藏
 [10] Sun, Xiaoyu.,Liu, Caixuan.,Lu, Xiao.,Ling, Zhiyang.,Yi, Chunyan.,...&Sun, Bing.(2022).Unique binding pattern for a lineage of human antibodies with broad reactivity against influenza A virus.NATURE COMMUNICATIONS,13(1).浏览/下载:947/295; 被引[WOS]:18; IF:14.7/16.1评论推荐收藏