Divinylsulfonamides as Specific Linkers for Stapling Disulfide Bonds in Peptides

doi:10.1021/acs.orglett.7b02464

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	Divinylsulfonamides as Specific Linkers for Stapling Disulfide Bonds in Peptides
	Li, Zhihong1,2,3 ; Huang, Rong1 ; Xu, Hongtao1,2 ; Chen, Jiakang1 ; Zhan, Yuexiong1 ; Zhou, Xianhao1 ; Chen, Hongli1 ; Jiang, Biao1
	2017-09-15
发表期刊	ORGANIC LETTERS (IF:4.9[JCR-2023],4.5[5-Year])
ISSN	1523-7060
卷号	19 期号:18 页码:4972-4975
发表状态	已发表
DOI	10.1021/acs.orglett.7b02464
摘要	A new class of N-phenyl-divinylsulfonamides which can be easily prepared have been successfully developed and utilized as efficient linkers in the field of disulfide bond modification. Functional divinylsulfonamides provide opportunities for the specific introduction of various functionalities, including affinity probes, fluorescent tags, and drugs, into peptides.
收录类别	SCI ; IC
语种	英语
资助项目	Open Foundation of the State Key Laboratory of Drug Research, China[SIMM1601KF-05]
WOS研究方向	Chemistry
WOS类目	Chemistry, Organic
WOS记录号	WOS:000411304300068
出版者	AMER CHEMICAL SOC
WOS关键词	CROSS-LINKING ; PROTEIN MODIFICATION ; MACROCYCLIZATION ; CONJUGATION ; PEGYLATION ; BIOCONJUGATION ; EFFICIENT ; POLYMERS ; MALEIMIDES
原始文献类型	Article
引用统计	正在获取...
文献类型	期刊论文
条目标识符	https://kms.shanghaitech.edu.cn/handle/2MSLDSTB/9903
专题	免疫化学研究所生命科学与技术学院免疫化学研究所_特聘教授组_抗体化学实验室免疫化学研究所_特聘教授组_抗体设计学实验室免疫化学研究所_公共科研平台_分析化学平台生命科学与技术学院_硕士生
通讯作者	Chen, Hongli; Jiang, Biao
作者单位	1.ShanghaiTech Univ, Shanghai Inst Adv Immunochem Studies, Shanghai 201210, Peoples R China 2.Chinese Acad Sci, Shanghai Inst Mat Med, State Key Lab Drug Res, Shanghai 201203, Peoples R China 3.Univ Chinese Acad Sci, Beijing 100049, Peoples R China
第一作者单位	免疫化学研究所
通讯作者单位	免疫化学研究所
第一作者的第一单位	免疫化学研究所
推荐引用方式 GB/T 7714	Li, Zhihong,Huang, Rong,Xu, Hongtao,et al. Divinylsulfonamides as Specific Linkers for Stapling Disulfide Bonds in Peptides[J]. ORGANIC LETTERS,2017,19(18):4972-4975.
APA	Li, Zhihong.,Huang, Rong.,Xu, Hongtao.,Chen, Jiakang.,Zhan, Yuexiong.,...&Jiang, Biao.(2017).Divinylsulfonamides as Specific Linkers for Stapling Disulfide Bonds in Peptides.ORGANIC LETTERS,19(18),4972-4975.
MLA	Li, Zhihong,et al."Divinylsulfonamides as Specific Linkers for Stapling Disulfide Bonds in Peptides".ORGANIC LETTERS 19.18(2017):4972-4975.