Discovery of Novel Macrocyclic Hedgehog Pathway Inhibitors Acting by Suppressing the Gli-Mediated Transcription

doi:10.1021/acs.jmedchem.7b01185

	Discovery of Novel Macrocyclic Hedgehog Pathway Inhibitors Acting by Suppressing the Gli-Mediated Transcription
	Liu, Gang 1,2,5; Huang, Wenjing 3; Wang, Juan 3; Liu, Xiaohua 1,2; Yang, Jun 3; Zhang, Yu 3; Geng, Yong 1,2,5; Tan, Wenfu 3; Zhang, Ao1,2,4,5
	2017-10-12
发表期刊	JOURNAL OF MEDICINAL CHEMISTRY (IF:6.8[JCR-2023],7.1[5-Year])
ISSN	0022-2623
卷号	60 期号:19 页码:8218-8245
发表状态	已发表
DOI	10.1021/acs.jmedchem.7b01185
摘要	[GRAPHICS]
收录类别	SCI ; IC
语种	英语
资助项目	CAS Key Laboratory of Receptor Research of SIMM[SIMM1606YKF-08] ; CAS Key Laboratory of Receptor Research of SIMM[SIMM1606YZZ-06]
WOS研究方向	Pharmacology & Pharmacy
WOS类目	Chemistry, Medicinal
WOS记录号	WOS:000413131400020
出版者	AMER CHEMICAL SOC
WOS关键词	BASAL-CELL CARCINOMA ; CANCER ; MEDULLOBLASTOMA ; GROWTH ; ACTIVATION ; RESISTANCE ; VISMODEGIB ; ANTAGONISTS ; SONIDEGIB ; STRATEGY
原始文献类型	Article
引用统计	正在获取...
文献类型	期刊论文
条目标识符	https://kms.shanghaitech.edu.cn/handle/2MSLDSTB/9891
专题	生命科学与技术学院_特聘教授组_张翱组
通讯作者	Tan, Wenfu; Zhang, Ao
作者单位	1.SIMM, CAS Key Lab Receptor Res, Shanghai 201203, Peoples R China 2.SIMM, State Key Lab Drug Res, Shanghai 201203, Peoples R China 3.Fudan Univ, Dept Pharmacol, Sch Pharm, Shanghai 201203, Peoples R China 4.ShanghaiTech Univ, Sch Life Sci & Technol, Shanghai 201210, Peoples R China 5.Univ Chinese Acad Sci, Beijing 100049, Peoples R China
通讯作者单位	生命科学与技术学院
推荐引用方式 GB/T 7714	Liu, Gang,Huang, Wenjing,Wang, Juan,et al. Discovery of Novel Macrocyclic Hedgehog Pathway Inhibitors Acting by Suppressing the Gli-Mediated Transcription[J]. JOURNAL OF MEDICINAL CHEMISTRY,2017,60(19):8218-8245.
APA	Liu, Gang.,Huang, Wenjing.,Wang, Juan.,Liu, Xiaohua.,Yang, Jun.,...&Zhang, Ao.(2017).Discovery of Novel Macrocyclic Hedgehog Pathway Inhibitors Acting by Suppressing the Gli-Mediated Transcription.JOURNAL OF MEDICINAL CHEMISTRY,60(19),8218-8245.
MLA	Liu, Gang,et al."Discovery of Novel Macrocyclic Hedgehog Pathway Inhibitors Acting by Suppressing the Gli-Mediated Transcription".JOURNAL OF MEDICINAL CHEMISTRY 60.19(2017):8218-8245.