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Revisit ligand-receptor interaction at the human vasopressin V 2 receptor: A kinetic perspective 期刊论文
EUROPEAN JOURNAL OF PHARMACOLOGY, 2020, 卷号: 880
Authors:  Liu, Chunji;  Xia, Leyi;  Fu, Kequan;  Cao, Xudong;  Yan, Wenzhong;  Cheng, Jianjun;  Roux, Thomas;  Peletier, Lambertus A.;  Yin, Xiaoxing;  Guo, Dong
Favorite  |  View/Download:28/0  |  Submit date:2020/07/06
Design and Synthesis of Bitopic 2-Phenylcyclopropylmethylamine (PCPMA) Derivatives as Selective Dopamine D3 Receptor Ligands 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2020, 卷号: 63, 期号: 9, 页码: 4579-4602
Authors:  Tan, Liang;  Zhou, Qingtong;  Yan, Wenzhong;  Sun, Jian;  Kozikowski, Alan P.;  Zhao, Suwen;  Huang, Xi-Ping;  Cheng, Jianjun
Favorite  |  View/Download:22/0  |  Submit date:2020/06/09
Haloperidol bound D-2 dopamine receptor structure inspired the discovery of subtype selective ligands 期刊论文
NATURE COMMUNICATIONS, 2020, 卷号: 11, 期号: 1
Authors:  Fan, Luyu;  Tan, Liang;  Chen, Zhangcheng;  Qi, Jianzhong;  Nie, Fen;  Luo, Zhipu;  Cheng, Jianjun;  Wang, Sheng
View  |  Adobe PDF(1448Kb)  |  Favorite  |  View/Download:6/1  |  Submit date:2020/09/23
Enhancing the Signaling of GPCRs via Orthosteric Ions 期刊论文
ACS CENTRAL SCIENCE, 2020, 卷号: 6, 期号: 2, 页码: 274-282
Authors:  Chan, H. C. Stephen;  Xu, Yueming;  Tan, Liang;  Vogel, Horst;  Cheng, Jianjun;  Wu, Dong;  Yuan, Shuguang
Favorite  |  View/Download:36/0  |  Submit date:2020/03/28
噻唑并环类化合物、其制备方法、中间体和应用 专利
申请号:CN201911152880.3,申请日期: 2019-11-22,类型:发明专利,状态:实质审查
Inventors:  程建军;  闫文仲
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三唑并环类化合物、其制备方法、中间体和应用 专利
申请号:CN201911153069.7,申请日期: 2019-11-22,类型:发明专利,状态:实质审查
Inventors:  程建军;  闫文仲
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TRIAZOLO CYCLE COMPOUND, PREPARATION METHOD THEREFOR, INTERMEDIATE THEREOF AND APPLICATION THEREOF 专利
申请号:WOCN19120284,申请日期: 2019-11-22,类型:发明专利,状态:暂缺
Inventors:  CHENG Jianjun;  YAN Wenzhong
View  |  Adobe PDF(6129Kb)  |  Favorite  |  View/Download:16/3  |  Submit date:2020/06/12
THIAZOLO RING COMPOUND, PREPARATION METHOD THEREFOR, INTERMEDIATE THEREOF, AND APPLICATION THEREOF 专利
申请号:WOCN19120259,申请日期: 2019-11-22,类型:发明专利,状态:暂缺
Inventors:  CHENG Jianjun;  YAN Wenzhong
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Design of fluorinated cyclopropane derivatives of 2-phenylcyclopropylmethylamine leading to identification of a selective serotonin 2C (5-HT2C) receptor agonist without 5-HT2B agonism 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 182
Authors:  Zhang, Guiping;  McCorvy, John D.;  Shen, Sida;  Cheng, Jianjun;  Roth, Bryan L.;  Kozikowski, Alan P.
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Dual-acting compounds targeting the adenosine 2A receptor (A2AR) and histone deacetylases (HDACs) for cancer immunotherapy 会议论文
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY
Authors:  Yan, Wenzhong;  Liu, Ruiquan;  Cheng, Jianjun
Favorite  |  View/Download:12/0  |  Submit date:2020/05/06