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Structural basis of ligand recognition and self-activation of orphan GPR52 期刊论文
NATURE, 2020
Authors:  Lin, Xi;  Li, Mingyue;  Wang, Niandong;  Wu, Yiran;  Luo, Zhipu;  Guo, Shimeng;  Han, Gye-Won;  Li, Shaobai;  Yue, Yang;  Wei, Xiaohu;  Xie, Xin;  Chen, Yong;  Zhao, Suwen;  Wu, Jian;  Lei, Ming;  Xu, Fei
Favorite  |  View/Download:68/0  |  Submit date:2020/03/16
孤儿受体GPR52晶体结构揭示配体结合新机制 期刊论文
生命的化学, 2020, 卷号: 40, 期号: 3, 页码: 313-318
Authors:  林浠;  徐菲
Favorite  |  View/Download:7/0  |  Submit date:2020/07/22
Colocalization Strategy Unveils an Underside Binding Site in the Transmembrane Domain of Smoothened Receptor 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 62, 期号: 21, 页码: 9983-9989
Authors:  Zhou, Fang;  Ding, Kang;  Zhou, Yiqing;  Liu, Yang;  Liu, Xiaoyan;  Zhao, Fei;  Wu, Yiran;  Zhang, Xianjun;  Tan, Qiwen;  Xu, Fei;  Tan, Wenfu;  Xiao, Youli;  Zhao, Suwen;  Tao, Houchao
Adobe PDF(2658Kb)  |  Favorite  |  View/Download:62/2  |  Submit date:2019/12/05
The structure-based traceless specific fluorescence labeling of the smoothened receptor 期刊论文
ORGANIC & BIOMOLECULAR CHEMISTRY, 2019, 卷号: 17, 期号: 25, 页码: 6136-6142
Authors:  Xue, Dongxiang;  Ye, Lintao;  Zheng, Jun;  Wu, Yiran;  Zhang, Xianjun;  Xu, Yueming;  Li, Tao;  Stevens, Raymond C.;  Xu, Fei;  Zhuang, Min;  Zhao, Suwen;  Zhao, Fei;  Tao, Houchao
Adobe PDF(1719Kb)  |  Favorite  |  View/Download:109/3  |  Submit date:2019/07/26
Determination of an underneath binding in the transmembrane domain of smoothened receptor 会议论文
JOURNAL OF BIOENERGETICS AND BIOMEMBRANES
Authors:  Zhou, F.;  Ding, K.;  Zhou, Y.;  Liu, Y.;  Liu, X.;  Zhao, F.;  Wu, Y.;  Zhang, X.;  Xu, F.;  Zhao, S.;  Tao, H.
Adobe PDF(157Kb)  |  Favorite  |  View/Download:122/9  |  Submit date:2019/02/27
Toward the first orphan GPCR structure 会议论文
JOURNAL OF BIOENERGETICS AND BIOMEMBRANES
Authors:  Lin, X.;  Xu, F.
Adobe PDF(71Kb)  |  Favorite  |  View/Download:74/6  |  Submit date:2019/02/27
Structural and Druggability Landscape of Frizzled G Protein-Coupled Receptors 期刊论文
TRENDS IN BIOCHEMICAL SCIENCES, 2018, 卷号: 43, 期号: 12, 页码: 1033-1046
Authors:  Zhang, Xianjun;  Dong, Shaowei;  Xu, Fei
Adobe PDF(4986Kb)  |  Favorite  |  View/Download:112/2  |  Submit date:2018/12/01
Apj(+) Vessels Drive Tumor Growth and Represent a Tractable Therapeutic Target 期刊论文
CELL REPORTS, 2018, 卷号: 25, 期号: 5, 页码: 1241-+
Authors:  Zhao, Huan;  Tian, Xueying;  He, Lingjuan;  Li, Yan;  Pu, Wenjuan;  Liu, Qiaozhen;  Tang, Juan;  Wu, Jiaying;  Cheng, Xin;  Liu, Yang;  Zhou, Qingtong;  Tan, Zhen;  Bai, Fan;  Xu, Fei;  Smart, Nicola;  Zhou, Bin
Adobe PDF(8779Kb)  |  Favorite  |  View/Download:83/1  |  Submit date:2018/11/15
Crystal structure of the Frizzled 4 receptor in a ligand-free state 期刊论文
NATURE, 2018, 卷号: 560, 期号: 7720, 页码: 666-+
Authors:  Yang, Shifan;  Wu, Yiran;  Xu, Ting-Hai;  de Waal, Parker W.;  He, Yuanzheng;  Pu, Mengchen;  Chen, Yuxiang;  DeBruine, Zachary J.;  Zhang, Bingjie;  Zaidi, Saheem A.;  Popov, Petr;  Guo, Yu;  Han, Gye Won;  Lu, Yang;  Suino-Powell, Kelly;  Dong, Shaowei;  Harikumar, Kaleeckal G.;  Miller, Laurence J.;  Katritch, Vsevolod;  Xu, H. Eric;  Shui, Wenqing;  Stevens, Raymond C.;  Melcher, Karsten;  Zhao, Suwen;  Xu, Fei
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Conserved salt-bridge competition triggered by phosphorylation regulates the protein interactome 期刊论文
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2017, 卷号: 114, 期号: 51, 页码: 13453-13458
Authors:  Skinner, John J.;  Wang, Sheng;  Lee, Jiyoung;  Ong, Colin;  Sommese, Ruth;  Sivaramakrishnan, Sivaraj;  Koelmel, Wolfgang;  Hirschbeck, Maria;  Schindelin, Hermann;  Kisker, Caroline;  Lorenz, Kristina;  Sosnick, Tobin R.;  Rosner, Marsha Rich
Adobe PDF(2024Kb)  |  Favorite  |  View/Download:121/2  |  Submit date:2018/01/05