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OTTM: an automated classification tool for translational drug discovery from omics data 期刊论文
BRIEFINGS IN BIOINFORMATICS, 2023
作者:  Yang, Xiaobo;  Zhang, Bei;  Wang, Siqi;  Lu, Ye;  Chen, Kaixian
Adobe PDF(1499Kb)  |  收藏  |  浏览/下载：118/22  |  提交时间：2023/08/28
Design, synthesis and biological evaluation of 2-aminopyridine derivatives as USP7 inhibitors 期刊论文
BIOORGANIC CHEMISTRY, 2022, 卷号: 129
作者:  Xu, Xiaoming;  Wang, Mingchen;  Xu, Hailong;  Liu, Na;  Chen, Kaixian
Adobe PDF(1691Kb)  |  收藏  |  浏览/下载：122/0  |  提交时间：2022/10/18
P300/CBP inhibition sensitizes mantle cell lymphoma to PI3K delta inhibitor idelalisib 期刊论文
ACTA PHARMACOLOGICA SINICA, 2022
作者:  Zhou, Xiao-ru;  Li, Xiao;  Liao, Li-ping;  Han, Jie;  Huang, Jing
Adobe PDF(5109Kb)  |  收藏  |  浏览/下载：169/0  |  提交时间：2021/05/14
High-Throughput-Methyl-Reading (HTMR) assay: a solution based on nucleotide methyl-binding proteins enables large-scale screening for DNA/RNA methyltransferases and demethylases 期刊论文
NUCLEIC ACIDS RESEARCH, 2022, 卷号: 50, 期号: 2
作者:  Xiao, Senhao;  Guo, Siqi;  Han, Jie;  Sun, Yanli;  Wang, Mingchen
Adobe PDF(2812Kb)  |  收藏  |  浏览/下载：414/95  |  提交时间：2022/03/29
Design, synthesis and biological evaluation of a novel spiro oxazolidinedione as potent p300/CBP HAT inhibitor for the treatment of ovarian cancer 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2021, 卷号: 52
作者:  Ding, Hong;  Pei, Yuan;  Li, Yuanqing;  Xu, Wen;  Mei, Lianghe
Adobe PDF(1319Kb)  |  收藏  |  浏览/下载：104/0  |  提交时间：2022/04/12
Drug repurposing against breast cancer by integrating drug-exposure expression profiles and drug-drug links based on graph neural network 期刊论文
BIOINFORMATICS, 2021, 卷号: 37, 期号: 18
作者:  Cui, Chen;  Ding, Xiaoyu;  Wang, Dingyan;  Chen, Lifan;  Xiao, Fu
Adobe PDF(370Kb)  |  收藏  |  浏览/下载：291/124  |  提交时间：2022/01/04
Identification of novel anti-inflammatory Nur77 modulators by virtual screening 期刊论文
BIOORGANIC CHEMISTRY, 2021, 卷号: 112
作者:  Ding, Xiaoyu;  Zhao, Zijie;  Wu, Yue;  Zhang, Hao;  Chen, Kaixian
Adobe PDF(2637Kb)  |  收藏  |  浏览/下载：139/0  |  提交时间：2021/07/02
Design, synthesis, and biological evaluation of 4-benzoylamino-1H-pyrazole-3-carboxamide derivatives as potent CDK2 inhibitors 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 215
作者:  Lin, Tingting;  Li, Jiacheng;  Liu, Liping;  Li, Yuanqing;  Jiang, Hualiang
Adobe PDF(2572Kb)  |  收藏  |  浏览/下载：173/0  |  提交时间：2021/08/16
Diversified strategy for the synthesis of DNA-encoded oxindole libraries 期刊论文
CHEMICAL SCIENCE, 2021, 卷号: 12, 期号: 8, 页码: 2841-2847
作者:  Wang, Xuan;  Liu, Jiaxiang;  Yan, Ziqin;  Liu, Xiaohong;  Liu, Sixiu
Adobe PDF(991Kb)  |  收藏  |  浏览/下载：493/159  |  提交时间：2021/04/19
Natural product 1,2,3,4,6-penta-O-galloyl-beta-D-glucopyranose is a reversible inhibitor of glyceraldehyde 3-phosphate dehydrogenase 期刊论文
ACTA PHARMACOLOGICA SINICA, 2021
作者:  Li, Wen;  Liao, Li-ping;  Song, Ning;  Liu, Yan-jun;  Ding, Yi-luan
Adobe PDF(3035Kb)  |  收藏  |  浏览/下载：206/0  |  提交时间：2021/05/14