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2-Phenylcyclopropylmethylamine Derivatives as Dopamine D-2 Receptor Partial Agonists: Design, Synthesis, and Biological Evaluation 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64, 期号: 23
Authors:  Yan, Wenzhong;  Fan, Luyu;  Yu, Jing;  Liu, Ruiquan;  Wang, Huan
Favorite  |  View/Download：19/0  |  Submit date：2022/02/28
Structure-Based Design of Dual-Acting Compounds Targeting Adenosine A(2A) Receptor and Histone Deacetylase as Novel Tumor Immunotherapeutic Agents 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64, 期号: 22
Authors:  Yan, Wenzhong;  Ling, Lijun;  Wu, Yiran;  Yang, Kexin;  Liu, Ruiquan
Favorite  |  View/Download：26/0  |  Submit date：2022/02/28
Rational Remodeling of Atypical Scaffolds for the Design of Photoswitchable Cannabinoid Receptor Tools 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64, 期号: 18, 页码: 13752-13765
Authors:  Hu, Tao;  Zheng, Guoxun;  Xue, Dongxiang;  Zhao, Simeng;  Li, Fei
Adobe PDF(4377Kb)  |  Favorite  |  View/Download：86/0  |  Submit date：2021/11/25
Carbon-silicon switch led to the discovery of novel synthetic cannabinoids with therapeutic effects in a mouse model of multiple sclerosis 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 226
Authors:  Duan, Wenwen;  Sun, Ying;  Wu, Meng;  Zhang, Zhiyuan;  Zhang, Taotao
Favorite  |  View/Download：78/0  |  Submit date：2021/11/05
Elucidation of Distinct Modular Assemblies of Smoothened Receptor by Bitopic Ligand Measurement 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64, 期号: 18, 页码: 13830-13840
Authors:  Zhao, Fei;  Wu, Yiran;  Zhou, Fang;  Xue, Dongxiang;  Zhao, Simeng
Favorite  |  View/Download：80/0  |  Submit date：2021/10/15
Pepper component 7-ethoxy-4-methylcoumarin, a novel dopamine D2 receptor agonist, ameliorates experimental Parkinson's disease in mice and Caenorhabditis elegans 期刊论文
PHARMACOLOGICAL RESEARCH, 2021, 卷号: 163, 页码: #VALUE!
Authors:  Li, Hongli;  Feng, Yaru;  Chen, Ziyu;  Jiang, Xi;  Zhou, Zhenyu
Favorite  |  View/Download：143/0  |  Submit date：2021/04/01
Structure-Activity Relationship Studies of Hydantoin-Cored Ligands for Smoothened Receptor 期刊论文
CHEMISTRYOPEN, 2021, 卷号: 10, 期号: 10, 页码: 1028-1032
Authors:  Liu, Yang;  Zhou, Fang;  Ding, Kang;  Xue, Dongxiang;  Zhu, Zhihao
Favorite  |  View/Download：54/0  |  Submit date：2021/12/03
Structural insights into the activation initiation of full-length mGlu1 期刊论文
PROTEIN & CELL, 2020
Authors:  Zhang, Jinyi;  Qu, Lu;  Wu, Lijie;  Tang, Xiaomeng;  Luo, Feng
View  |  Adobe PDF(986Kb)  |  Favorite  |  View/Download：277/36  |  Submit date：2021/01/19
Tumor Immunotherapy Using A(2A) Adenosine Receptor Antagonists 期刊论文
PHARMACEUTICALS, 2020, 卷号: 13, 期号: 9
Authors:  Zhang, Jinfeng;  Yan, Wenzhong;  Duan, Wenwen;  Wuthrich, Kurt;  Cheng, Jianjun
View  |  Adobe PDF(2336Kb)  |  Favorite  |  View/Download：196/48  |  Submit date：2020/11/24
Structural basis of CXC chemokine receptor 2 activation and signalling 期刊论文
NATURE, 2020
Authors:  Liu, Kaiwen;  Wu, Lijie;  Yuan, Shuguang;  Wu, Meng;  Xu, Yueming
Favorite  |  View/Download：237/0  |  Submit date：2020/09/15