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A Mems-Based Flexible Bidirectional Multiregion Neural Interface for Olfactory Augmentation
2025
会议录名称2025 IEEE 38TH INTERNATIONAL CONFERENCE ON MICRO ELECTRO MECHANICAL SYSTEMS (MEMS)
ISSN1084-6999
发表状态已发表
DOI10.1109/MEMS61431.2025.10917478
摘要

This paper reports a flexible and bidirectional olfactory neural interface based on microelectromechanical systems fabrication process and the demonstrations of cross-regional synchronous recording and olfactory augmentation on free-moving mice. With overall 4-μm-thick microelectrodes and a compact headstage mounted on the skull, it enables long-term electrophysiological recording and electrostimulation of the olfactory neural pathways of mice, including the olfactory epithelium, the olfactory bulb and the olfactory cortex. Our results demonstrate the broad application potential of this multiregion olfactory neural interface in studying functional connectivity within the olfactory neural network, investigating olfactory navigation behaviors, optimizing parameters for micro-electrostimulation-induced olfactory augmentation, and exploring the underlying mechanisms.

会议地点Kaohsiung, Taiwan
会议日期19-23 Jan. 2025
URL查看原文
来源库IEEE
文献类型会议论文
条目标识符https://kms.shanghaitech.edu.cn/handle/2MSLDSTB/503621
专题物质科学与技术学院
物质科学与技术学院_特聘教授组_陶虎组
作者单位
1.2020 X-Lab, Shanghai Institute of Microsystem and Information Technology, Chinese Academy of Sciences, Shanghai, China
2.School of Graduate Study, University of Chinese Academy of Sciences, Beijing, China
3.State Key Laboratory of Transducer Technology, Shanghai Institute of Microsystem and Information Technology, Chinese Academy of Sciences, Shanghai, China
4.Neuroxess Co., Ltd., Shanghai, China
5.Center of Materials Science and Optoelectronics Engineering, University of Chinese Academy of Sciences, Beijing, China
6.School of Physical Science and Technology, ShanghaiTech University, Shanghai, China
7.Center for Excellence in Brain Science and Intelligence Technology, Chinese Academy of Sciences, Shanghai, China
8.Guangdong Institute of Intelligence Science and Technology, Zhuhai, China
9.Tianqiao and Chrissy Chen Institute for Translational Research, Shanghai, China
推荐引用方式
GB/T 7714
Jizhi Liang,Hailang He,Yuxin Liu,et al. A Mems-Based Flexible Bidirectional Multiregion Neural Interface for Olfactory Augmentation[C],2025.
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