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A bioinspired microbial taste chip with artificial intelligence-enabled high selectivity and ultra-short response time
2025-06-01
发表期刊BIOSENSORS & BIOELECTRONICS (IF:10.7[JCR-2023],9.9[5-Year])
ISSN0956-5663
EISSN1873-4235
卷号277
发表状态已发表
DOI10.1016/j.bios.2025.117264
摘要

Real-time water pollution monitoring is crucial as global water pollution has become an urgent issue endangering the health of humanity. Microbial taste chips are promising for water pollution monitoring due to the advantages of short response time and real-time monitoring capability. However, although more than 200 journal research articles on microbial taste chips have been reported to date, sensor selectivity, which is the foremost critical parameter, remains an unsolved challenge even after utilizing gene-editing techniques. In addition, the response time is long and takes at least 3 min. Herein, we report a breakthrough to solve the selectivity challenge by a bioinspired wireless microfluidic microbial taste chip with artificial-intelligence(AI)-enabled high selectivity. Utilizing gated recurrent unit(GRU)-based deep learning algorithms, we demonstrate a classification accuracy of 98.9% for Cu2+, Pb2+, and Cr6+ by harnessing the different temporal output current patterns of the chips to different pollutants. A shortest 48-s response time is achieved, 3.75 times shorter than the fastest previously reported counterpart. The chip enables real-time sensing of Cu2+, Pb2+, and Cr6+ with high accuracy and linearity. Combined with a small footprint and wireless connectivity, the chip may find applications in real-time quantitative heavy metal ions in water monitoring and contribute to global efforts in fighting water pollution.

关键词Taste chip Sensor selectivity Microfluidics Artificial intelligence (AI) Gated recurrent unit (GRU)
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收录类别SCI ; EI
语种英语
资助项目National Natural Science Foundation of China[
WOS研究方向Biophysics ; Biotechnology & Applied Microbiology ; Chemistry ; Electrochemistry ; Science & Technology - Other Topics
WOS类目Biophysics ; Biotechnology & Applied Microbiology ; Chemistry, Analytical ; Electrochemistry ; Nanoscience & Nanotechnology
WOS记录号WOS:001432197600001
出版者ELSEVIER ADVANCED TECHNOLOGY
EI入藏号20250817924737
EI主题词Microfluidics
EI分类号1401.4.1 Microfluidics - 1502.1.1.4.2 Water Pollution Control
原始文献类型Journal article (JA)
文献类型期刊论文
条目标识符https://kms.shanghaitech.edu.cn/handle/2MSLDSTB/496873
专题信息科学与技术学院
信息科学与技术学院_硕士生
信息科学与技术学院_本科生
信息科学与技术学院_博士生
信息科学与技术学院_PI研究组_任豪组
通讯作者Ren, Hao
作者单位
1.ShanghaiTech Univ, Sch Informat Sci & Technol, Shanghai 201210, Peoples R China
2.ShanghaiTech Univ, Shanghai Engn Res Ctr Energy Efficient & Custom AI, Shanghai 201210, Peoples R China
第一作者单位信息科学与技术学院
通讯作者单位信息科学与技术学院;  上海科技大学
第一作者的第一单位信息科学与技术学院
推荐引用方式
GB/T 7714
Wang, Yining,Tang, Fengxiang,Liu, Boya,et al. A bioinspired microbial taste chip with artificial intelligence-enabled high selectivity and ultra-short response time[J]. BIOSENSORS & BIOELECTRONICS,2025,277.
APA Wang, Yining,Tang, Fengxiang,Liu, Boya,Wu, Yifan,Zhang, Ruohan,&Ren, Hao.(2025).A bioinspired microbial taste chip with artificial intelligence-enabled high selectivity and ultra-short response time.BIOSENSORS & BIOELECTRONICS,277.
MLA Wang, Yining,et al."A bioinspired microbial taste chip with artificial intelligence-enabled high selectivity and ultra-short response time".BIOSENSORS & BIOELECTRONICS 277(2025).
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