上海科技大学知识管理系统

The infant brain rapidly matures after birth with distinct brain regions interconnecting for unique functions at different developmental stages, underpinning different behavioral milestones. A critical knowledge gap is how the interweaved relation between brain structure and function evolves during early development and whether such relation can predict later outcomes. Most previous studies focused on the youths or adults, holding divergent views on how such a relationship is built in infancy. We systematically studied infant brain structure-function coupling, including its spatial and longitudinal patterns, hemispheric lateralization, and the association with developmental scores such as fine motor skills. Our findings provide insights into how the infant brain's wiring influences brain functioning and behavior.