上海科技大学知识管理系统

 By using a newly developed 4-hydroxy picolinohydrazide as the ligand, Cu-catalyzed coupling of (hetero)aryl chlorides with sodium aryl sulfonates proceeded smoothly at 130 oC to give a series of biarylsulfones in 53-96% yields. This represent the first metal-catalyzed coupling reaction of (hetero)aryl chlorides with sodium aryl sulfonates. Aryl and heteroaryl chlorides bearing either electron-donating or electron-withdrawing groups were applicable for this coupling reaction.