Radical Copolymerization of 2-Thiocyanatoethyl Substituted Acrylate to Introduce Thiol-Acrylate-Based Dynamic Bonds as Degradable Linker

doi:10.1002/pol.20240545

	Radical Copolymerization of 2-Thiocyanatoethyl Substituted Acrylate to Introduce Thiol-Acrylate-Based Dynamic Bonds as Degradable Linker
	Ye, Feiyang; Yue, Chaowei; Li, Yifan
	2025
发表期刊	JOURNAL OF POLYMER SCIENCE (IF:3.9[JCR-2023],3.7[5-Year])
ISSN	2642-4150
EISSN	2642-4169
卷号	63 期号:1 页码:263-269
发表状态	已发表
DOI	10.1002/pol.20240545
摘要	We employ the 1,4-cyano group migration radical polymerization strategy to copolymerize acrylates with 2-thiocyanate ethyl substituted acrylates. The radical copolymerization can be effectively controlled using reversible addition-fragmentation chain-transfer (RAFT) polymerization. This approach can incorporate thiol-acrylate-based dynamic bonds within the polymer main chain. Utilizing these dynamic bonds, we degrade the polymers under mild basic conditions, achieved with the assistance of 1,8-diazabicyclo[5.4.0]undec-7-ene (DBU) to facilitate the reversible thiol-Michael addition. Notably, high degradation efficiency is observed. This study exemplifies the application of 2-thiocyanate ethyl substituted acrylate in radical copolymerization to produce degradable polymers.
关键词	1,4-cyano group migration controlled radical polymerization degradation thiol-Michael addition-elimination
URL	查看原文
收录类别	SCI ; EI
语种	英语
WOS研究方向	Polymer Science
WOS类目	Polymer Science
WOS记录号	WOS:001343094600001
出版者	WILEY
EI入藏号	20244517311977
EI主题词	Copolymerization
EI分类号	205.2 ; 804.1 Organic Compounds
原始文献类型	Article in Press
文献类型	期刊论文
条目标识符	https://kms.shanghaitech.edu.cn/handle/2MSLDSTB/445512
专题	物质科学与技术学院物质科学与技术学院_硕士生物质科学与技术学院_PI研究组_李一凡组
通讯作者	Li, Yifan
作者单位	ShanghaiTech Univ, Sch Phys Sci & Technol, Shanghai, Peoples R China
第一作者单位	物质科学与技术学院
通讯作者单位	物质科学与技术学院
第一作者的第一单位	物质科学与技术学院
推荐引用方式 GB/T 7714	Ye, Feiyang,Yue, Chaowei,Li, Yifan. Radical Copolymerization of 2-Thiocyanatoethyl Substituted Acrylate to Introduce Thiol-Acrylate-Based Dynamic Bonds as Degradable Linker[J]. JOURNAL OF POLYMER SCIENCE,2025,63(1):263-269.
APA	Ye, Feiyang,Yue, Chaowei,&Li, Yifan.(2025).Radical Copolymerization of 2-Thiocyanatoethyl Substituted Acrylate to Introduce Thiol-Acrylate-Based Dynamic Bonds as Degradable Linker.JOURNAL OF POLYMER SCIENCE,63(1),263-269.
MLA	Ye, Feiyang,et al."Radical Copolymerization of 2-Thiocyanatoethyl Substituted Acrylate to Introduce Thiol-Acrylate-Based Dynamic Bonds as Degradable Linker".JOURNAL OF POLYMER SCIENCE 63.1(2025):263-269.