The Impact of Developmental and Metabolic Cues on Cytoophidium Formation
2024-09-01
发表期刊INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (IF:4.9[JCR-2023],5.6[5-Year])
ISSN1661-6596
EISSN1422-0067
卷号25期号:18
发表状态已发表
DOI10.3390/ijms251810058
摘要

The cytoophidium, composed mainly of CTP synthase (CTPS), is a newly discovered dynamic filamentous structure in various organisms such as archaea, bacteria, and humans. These filamentous structures represent a fascinating example of intracellular compartmentation and dynamic regulation of metabolic enzymes. Currently, cytoophidia have been proven to be tightly regulated and highly dynamic, responding rapidly to developmental and metabolic cues and playing a critical role in maintaining cellular homeostasis. In this review, we would like to discuss in detail the characteristics, mechanisms, functions, and potential applications of this conservative but promising organelle.

关键词cytoophidium CTP synthase compartmentation metabolic regulation developmental cue
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收录类别SCI
语种英语
资助项目National Natural Science Foundation of China[
WOS研究方向Biochemistry & Molecular Biology ; Chemistry
WOS类目Biochemistry & Molecular Biology ; Chemistry, Multidisciplinary
WOS记录号WOS:001323901600001
出版者MDPI
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文献类型期刊论文
条目标识符https://kms.shanghaitech.edu.cn/handle/2MSLDSTB/433519
专题生命科学与技术学院
生命科学与技术学院_PI研究组_刘冀珑组
生命科学与技术学院_博士生
通讯作者Zhang, Yuanbing; Liu, Ji-Long
作者单位
1.ShanghaiTech Univ, Sch Life Sci & Technol, Shanghai 201210, Peoples R China
2.Nanchang Univ, Affiliated Hosp 1, Jiangxi Med Coll, Ctr Expt Med, Nanchang 330006, Peoples R China
3.Shanghai Clin Res & Trial Ctr, Shanghai 201210, Peoples R China
4.Univ Oxford, Dept Physiol Anat & Genet, Oxford OX1 3PT, England
第一作者单位生命科学与技术学院
通讯作者单位生命科学与技术学院
第一作者的第一单位生命科学与技术学院
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GB/T 7714
Zhang, Yuanbing,Liu, Ji-Long. The Impact of Developmental and Metabolic Cues on Cytoophidium Formation[J]. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES,2024,25(18).
APA Zhang, Yuanbing,&Liu, Ji-Long.(2024).The Impact of Developmental and Metabolic Cues on Cytoophidium Formation.INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES,25(18).
MLA Zhang, Yuanbing,et al."The Impact of Developmental and Metabolic Cues on Cytoophidium Formation".INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 25.18(2024).
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