上海科技大学知识管理系统

PCCT can measure the energy of each detected X-ray photon and can differentiate between materials and tissues in ultra-high-resolution (UHR) mode. However, while current material decomposition methods have been evaluated at the standard resolution, material decomposition in UHR mode has not been fully explored. The performance of UHR material decomposition could be degraded in practice due to the non-uniform detector spectral response from the misalignment between the anti-scatter grid and the detector pixel array. In this paper, we propose a material decomposition method in UHR mode based on a physics-guided foundation model, including pixel-specific quantum sensitivity, charging sharing effect, pulse pile-up effect, and scattering.