Neuromuscular disease auxiliary diagnosis using a portable magnetomyographic system

doi:10.1088/1361-6579/ad65b0

	Neuromuscular disease auxiliary diagnosis using a portable magnetomyographic system
	Wei, Yutong1,3,4 ; Chen, Yan 2; Ye, Chaofeng1
	2024-09-01
发表期刊	PHYSIOLOGICAL MEASUREMENT (IF:2.3[JCR-2023],2.6[5-Year])
ISSN	0967-3334
EISSN	1361-6579
卷号	45 期号:9
发表状态	已发表
DOI	10.1088/1361-6579/ad65b0
摘要	Objective. The measurement of electromyography (EMG) signals with needle electrodes is widely used in clinical settings for diagnosing neuromuscular diseases. Patients experience pain during needle EMG testing. It is significant to develop alternative diagnostic modalities. Approach. This paper proposes a portable magnetomyography (MMG) measurement system for neuromuscular disease auxiliary diagnosis. Firstly, the design and operating principle of the system are introduced. The feasibility of using the system for auxiliary diagnosis of neuromuscular diseases is then studied. The magnetic signals and needle EMG signals of thirty subjects were collected and compared. Main results. It is found that the amplitude of muscle magnetic field signal increases during mild muscle contraction, and the signal magnitudes of the patients are smaller than those of normal subjects. The diseased muscles tested in the experiment can be distinguished from the normal muscles based on the signal amplitude, using a threshold value of 6 pT. The MMG diagnosis results align well with the needle EMG diagnosis. In addition, the MMG measurement indicates that there is a persistence of spontaneous activity in the diseased muscle. Significance. The experimental results demonstrate that it is feasible to auxiliary diagnose neuromuscular diseases using the portable MMG system, which offers the advantages of non-contact and painless measurements. After more in-depth, systematic, and quantitative research, the portable MMG could potentially be used for auxiliary diagnosis of neuromuscular diseases. The clinical trial registration number is ChiCTR2200067116.
关键词	neuromuscular disease auxiliary diagnosis bio-magnetic field measurement optically pumped magnetometer portable system
URL	查看原文
收录类别	SCI ; EI
语种	英语
资助项目	National Natural Science Foundation of Chinahttp://dx.doi.org/10.13039/501100001809[52277014]
WOS研究方向	Biophysics ; Engineering ; Physiology
WOS类目	Biophysics ; Engineering, Biomedical ; Physiology
WOS记录号	WOS:001306581500001
出版者	IOP Publishing Ltd
EI入藏号	20243717025586
EI主题词	Needles
EI分类号	101.2 ; 102.1 ; 102.1.2 ; 102.1.2.1 ; 213.6 ; 701.1 Electricity: Basic Concepts and Phenomena ; 701.2 Magnetism: Basic Concepts and Phenomena ; 709 Electrical Engineering, General ; 746 Imaging Techniques ; 941.4 Optical Variables Measurements ; 942.1.5
原始文献类型	Journal article (JA)
文献类型	期刊论文
条目标识符	https://kms.shanghaitech.edu.cn/handle/2MSLDSTB/421330
专题	信息科学与技术学院信息科学与技术学院_PI研究组_叶朝锋组信息科学与技术学院_博士生
通讯作者	Chen, Yan; Ye, Chaofeng
作者单位	1.ShanghaiTech Univ, Sch Informat Sci & Technol, Shanghai 201210, Peoples R China 2.Tongji Univ, Tongji Hosp, Sch Med, Dept Neurol, Shanghai 200065, Peoples R China 3.Chinese Acad Sci, Shanghai Inst Microsyst & Informat Technol, Shanghai, Peoples R China 4.Univ Chinese Acad Sci, Beijing, Peoples R China
第一作者单位	信息科学与技术学院
通讯作者单位	信息科学与技术学院
第一作者的第一单位	信息科学与技术学院
推荐引用方式 GB/T 7714	Wei, Yutong,Chen, Yan,Ye, Chaofeng. Neuromuscular disease auxiliary diagnosis using a portable magnetomyographic system[J]. PHYSIOLOGICAL MEASUREMENT,2024,45(9).
APA	Wei, Yutong,Chen, Yan,&Ye, Chaofeng.(2024).Neuromuscular disease auxiliary diagnosis using a portable magnetomyographic system.PHYSIOLOGICAL MEASUREMENT,45(9).
MLA	Wei, Yutong,et al."Neuromuscular disease auxiliary diagnosis using a portable magnetomyographic system".PHYSIOLOGICAL MEASUREMENT 45.9(2024).