Template-Guided Silicon Micromotor Assembly for Enhanced Cell Manipulation
2024-06-01
发表期刊ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (IF:16.1[JCR-2023],16.2[5-Year])
ISSN1433-7851
EISSN1521-3773
卷号63期号:28
发表状态已发表
DOI10.1002/anie.202405895
摘要

["Light-driven micro/nanorobots (LMNRs) are tiny, untethered machines with great potential in fields like precision medicine, nano manufacturing, and various other domains. However, their practicality hinges on developing light-manipulation strategies that combine versatile functionalities, flexible design options, and precise controllability. Our study introduces an innovative approach to construct micro/nanorobots (MNRs) by utilizing micro/nanomotors as fundamental building blocks. Inspired by silicon Metal-Insulator-Semiconductor (MIS) solar cell principles, we design a new type of optomagnetic hybrid micromotors (OHMs). These OHMs have been skillfully optimized with integrated magnetic constituent, resulting in efficient light propulsion, precise magnetic navigation, and the potential for controlled assembly. One of the key features of the OHMs is their ability to exhibit diverse motion modes influenced by fracture surfaces and interactions with the environment, streamlining cargo conveyance along \"micro expressway\"-the predesigned microchannels. Further enhancing their versatility, a template-guided assembly strategy facilitates the assembly of these micromotors into functional microrobots, encompassing various configurations such as \"V-shaped\", \"N-shaped\", and 3D structured microrobots. The heightened capabilities of these microrobots, underscore the innovative potential inherent in hybrid micromotor design and assembly, which provides a foundational platform for the realization of multi-component microrobots. Our work moves a step toward forthcoming microrobotic entities boasting advanced functionalities.","An optomagnetic hybrid micromotor was developed using an optimized silicon-based Metal-Insulator-Semiconductor (MIS) solar cell. The micromotor displays diverse motion modes influenced by fracture surfaces and interactions with the environment. Additionally, an innovative hole-assisted assembly strategy is introduced, facilitating assembly into functional microrobots and enabling precise cell manipulation. image"]

关键词silicon micromotor optomagnetic micromotor interaction behaviors assembled microrobots cell manipulation
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收录类别SCI ; EI
语种英语
资助项目the National Natural Science Foundation of China[
WOS研究方向Chemistry
WOS类目Chemistry, Multidisciplinary
WOS记录号WOS:001237411900001
出版者WILEY-V C H VERLAG GMBH
EI入藏号20242316204352
EI主题词Metal insulator boundaries
EI分类号461.9 Biology ; 705.3 Electric Motors ; 714.2 Semiconductor Devices and Integrated Circuits
原始文献类型Article in Press
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文献类型期刊论文
条目标识符https://kms.shanghaitech.edu.cn/handle/2MSLDSTB/387280
专题生物医学工程学院
生物医学工程学院_PI研究组_熊泽组
通讯作者Wang, Jizhuang; Li, Dan
作者单位
1.Jinan Univ, Coll Chem & Mat Sci, Guangdong Prov Key Lab Funct Supramol Coordinat Ma, Guangzhou 510632, Guangdong, Peoples R China
2.ShanghaiTech Univ, Sch Biomed Engn, Wireless & Smart Bioelect Lab, Shanghai 201210, Peoples R China
3.Univ Hong Kong, Dept Chem, Pokfulam Rd, Hong Kong, Peoples R China
4.Third Peoples Hosp Ganzhou, Ganzhou 341000, Jiangxi, Peoples R China
推荐引用方式
GB/T 7714
Gao, Yuxin,Ou, Leyan,Liu, Kunfeng,et al. Template-Guided Silicon Micromotor Assembly for Enhanced Cell Manipulation[J]. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION,2024,63(28).
APA Gao, Yuxin.,Ou, Leyan.,Liu, Kunfeng.,Guo, Yuan.,Li, Wanyuan.,...&Li, Dan.(2024).Template-Guided Silicon Micromotor Assembly for Enhanced Cell Manipulation.ANGEWANDTE CHEMIE-INTERNATIONAL EDITION,63(28).
MLA Gao, Yuxin,et al."Template-Guided Silicon Micromotor Assembly for Enhanced Cell Manipulation".ANGEWANDTE CHEMIE-INTERNATIONAL EDITION 63.28(2024).
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