High-Performance PMN-PT Single-Crystal-Based 1-3 Composite Transducer Integrated with a Biopsy Needle

doi:10.3390/bios14020074

	High-Performance PMN-PT Single-Crystal-Based 1-3 Composite Transducer Integrated with a Biopsy Needle
	Kreager, Benjamin C.1; Wu, Huaiyu 1; Chang, Wei-Yi 2; Moon, Sunho 1; Mitchell, Josh 1; Peng, Chang3 ; Huang, Chih-Chung 4; Muller, Marie 1; Tian, Jian 2; Jiang, Xiaoning 1
	2024-02
发表期刊	BIOSENSORS (IF:4.9[JCR-2023],5.2[5-Year])
EISSN	2079-6374
卷号	14 期号:2
DOI	10.3390/bios14020074
摘要	To address the need for high-resolution imaging in lung nodule detection and overcome the limitations of the shallow imaging depth associated with high-frequency ultrasound and the complex structure of lung tissue, we successfully integrated 50 MHz ultrasound transducers with 18-gauge biopsy needles. Featuring a miniaturized size of 0.6 × 0.5 × 0.5 mm3, the 50 MHz micromachined 1-3 composite transducer was tested to perform mechanical scanning of a nodule within a lung-tissue-mimicking phantom in vitro. The high-frequency transducer demonstrated the ability to achieve imaging with an axial resolution of 30 μm for measuring nodule edges. Moreover, the integrated biopsy needle prototype exhibited high accuracy (1.74% discrepancy) in estimating nodule area compared to actual dimensions in vitro. These results underscore the promising potential of biopsy-needle-integrated transducers in enhancing the accuracy of endoscopic ultrasound-guided fine needle aspiration biopsy (EUS-FNA) for clinical applications. © 2024 by the authors.
关键词	Biological organs Needles Single crystals Tissue Ultrasonic imaging Ultrasonic transducers 1-3 composites Biopsy needle Composite transducers Fine-needle aspirations High-frequency ultrasound Imaging-guided biopsy In-vitro Lung tissue Piezoelectric Ultrasound imaging
URL	查看原文
收录类别	EI
语种	英语
出版者	Multidisciplinary Digital Publishing Institute (MDPI)
EI入藏号	20240915634624
EI主题词	Biopsy
EI分类号	461.2 Biological Materials and Tissue Engineering ; 461.6 Medicine and Pharmacology ; 753.2 Ultrasonic Devices ; 933.1 Crystalline Solids
原始文献类型	Journal article (JA)
引用统计	被引频次：2[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	https://kms.shanghaitech.edu.cn/handle/2MSLDSTB/349962
专题	生物医学工程学院生物医学工程学院_PI研究组_彭畅组
通讯作者	Jiang, Xiaoning
作者单位	1.Department of Mechanical and Aerospace Engineering, North Carolina State University, Raleigh; NC; 27695, United States; 2.CTS Advanced Materials, 4925 Indiana Ave, Lisle; IL; 604532, United States; 3.School of Biomedical Engineering, ShanghaiTech University, Shanghai; 201210, China; 4.Department of Biomedical Engineering, National Cheng Kung University, Tainan; 701, Taiwan
推荐引用方式 GB/T 7714	Kreager, Benjamin C.,Wu, Huaiyu,Chang, Wei-Yi,et al. High-Performance PMN-PT Single-Crystal-Based 1-3 Composite Transducer Integrated with a Biopsy Needle[J]. BIOSENSORS,2024,14(2).
APA	Kreager, Benjamin C..,Wu, Huaiyu.,Chang, Wei-Yi.,Moon, Sunho.,Mitchell, Josh.,...&Jiang, Xiaoning.(2024).High-Performance PMN-PT Single-Crystal-Based 1-3 Composite Transducer Integrated with a Biopsy Needle.BIOSENSORS,14(2).
MLA	Kreager, Benjamin C.,et al."High-Performance PMN-PT Single-Crystal-Based 1-3 Composite Transducer Integrated with a Biopsy Needle".BIOSENSORS 14.2(2024).