β-L-Rhamnosylation and β-D-Mannosylation Mediated by 4-O-Ester Groups in Weakly Nucleophilic Environment

doi:10.26434/chemrxiv-2023-sg04q

	β-L-Rhamnosylation and β-D-Mannosylation Mediated by 4-O-Ester Groups in Weakly Nucleophilic Environment
	Zhang, Yongliang 1,2; Chen, Changsheng 1,2; Gao, Yongtao 1,2; Yang, Min3 ; He, Zehuan 1,2; Zhang, Bangzhi 5; Gu, Guofeng 1,2; Tang, Bencan 4; Cai, Feng 1,2,5
	2023-08-04
状态	已发表
摘要	Eq-4-O-acyl group directed β-rhamnosylation and β-mannosylation are achieved in carborane or BARF anion formed weakly nucleophilic environment with the assistance of a 2,3-orthocarbonate group. The 4-O-acyl group plays a critical role in directing the β-selectivity, and the weakly coordinating anion is essential to amplify this direction. The orthocarbonate group could be readily removed with 1,3-propanediol in the presence of BF3.Et2O.
关键词	Glycosylation &beta &beta Neighboring group participation -rhamnosylation -mannosylation Non-coordinating anion
DOI	10.26434/chemrxiv-2023-sg04q
相关网址	查看原文
出处	chemRxiv
WOS记录号	PPRN:74244011
WOS类目	Chemistry, Multidisciplinary
资助项目	National Natural Science Foundation of China[
文献类型	预印本
条目标识符	https://kms.shanghaitech.edu.cn/handle/2MSLDSTB/348065
专题	物质科学与技术学院_公共科研平台_分析测试平台
作者单位	1.Shandong Univ, Natl Glycoengn Res Ctr, 72 Binhai Rd, Qingdao 266237, Peoples R China 2.Shandong Univ, Shandong Key Lab Carbohydrate Chem & Glycobiol, 72 Binhai Rd, Qingdao 266237, Peoples R China 3.ShanghaiTech Univ, Ctr Anal & Characterizat, Sch Phys Sci & Technol, 393 Huaxia Middle Rd, Shanghai 201210, Peoples R China 4.Univ Nottingham Ningbo China, Fac Sci & Engn, 199 Taikang E Rd, Ningbo 315100, Peoples R China 5.Lanzhou Univ, Sch Basic Med Sci, Key Lab Preclin Study New Drugs Gansu Prov, Lanzhou 730000, Peoples R China
推荐引用方式 GB/T 7714	Zhang, Yongliang,Chen, Changsheng,Gao, Yongtao,et al. β-L-Rhamnosylation and β-D-Mannosylation Mediated by 4-O-Ester Groups in Weakly Nucleophilic Environment. 2023.