Effect of long-term Tai Chi training on Parkinson's disease: a 3.5-year follow-up cohort study

doi:10.1136/jnnp-2022-330967

KMS > 免疫化学研究所

	Effect of long-term Tai Chi training on Parkinson's disease: a 3.5-year follow-up cohort study
	Li, Gen 1,2; Huang, Pei 1,2; Cui, Shishuang 1,2; He, Yachao 1,2; Tan, Yuyan 1,2; Chen, Shengdi1,2,3
	2023-09-01
发表期刊	JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY
ISSN	0022-3050
EISSN	1468-330X
发表状态	已发表
DOI	10.1136/jnnp-2022-330967
摘要	Background Tai Chi has shown beneficial effects on the motor and non-motor symptoms of Parkinson's disease (PD), but no study has reported the effect of long-term Tai Chi training.Objective To examine whether long-term Tai Chi training can maintain improvement in patients with PD.Methods Cohorts of patients with PD with Tai Chi training (n=143) and patients with PD without exercise as a control group (n=187) were built from January 2016. All subjects were assessed at baseline and in November 2019, October 2020 and June 2021. A logarithmic linear model was used to analyse rating scales for motor and non-motor symptoms. The need to increase antiparkinsonian therapies was presented as a Kaplan-Meier plot and as a box plot. The bootstrap method was used to resample for statistical estimation.Results Tai Chi training reduced the annual changes in the deterioration of the Unified Parkinson's Disease Rating Scale and delayed the need for increasing antiparkinsonian therapies. The annual increase in the levodopa equivalent daily dosage was significantly lower in the Tai Chi group. Moreover, patients benefited from Tai Chi training in motor symptoms, non-motor symptoms and complications.Conclusion Tai Chi training has a long-term beneficial effect on PD, with an improvement in motor and non-motor symptoms and reduced complications.Trial registration number NCT05447975.
关键词	Parkinson's disease movement disorders neuroepidemiology rehabilitation
URL	查看原文
收录类别	SCI
语种	英语
WOS研究方向	Neurosciences & Neurology ; Psychiatry ; Surgery
WOS类目	Clinical Neurology ; Psychiatry ; Surgery
WOS记录号	WOS:001091231600001
出版者	BMJ PUBLISHING GROUP
引用统计	正在获取...
文献类型	期刊论文
条目标识符	https://kms.shanghaitech.edu.cn/handle/2MSLDSTB/345894
专题	免疫化学研究所免疫化学研究所_特聘教授组_陈生弟组
通讯作者	Huang, Pei; Tan, Yuyan; Chen, Shengdi
作者单位	1.Shanghai Jiao Tong Univ, Dept Neurol, Sch Med, Shanghai, Peoples R China 2.Shanghai Jiao Tong Univ, Ruijin Hosp, Inst Neurol, Sch Med, Shanghai, Peoples R China 3.Shanghai Tech Univ, Shanghai Inst Adv Immunochem Studies SIAIS, Lab Translat Res Neurodegenerat Dis, Shanghai, Peoples R China
通讯作者单位	免疫化学研究所
推荐引用方式 GB/T 7714	Li, Gen,Huang, Pei,Cui, Shishuang,et al. Effect of long-term Tai Chi training on Parkinson's disease: a 3.5-year follow-up cohort study[J]. JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY,2023.
APA	Li, Gen,Huang, Pei,Cui, Shishuang,He, Yachao,Tan, Yuyan,&Chen, Shengdi.(2023).Effect of long-term Tai Chi training on Parkinson's disease: a 3.5-year follow-up cohort study.JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY.
MLA	Li, Gen,et al."Effect of long-term Tai Chi training on Parkinson's disease: a 3.5-year follow-up cohort study".JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY (2023).