Enabling both time-domain and frequency-domain photoacoustic imaging by a fingertip laser diode system

doi:10.1364/OL.44.001988

	Enabling both time-domain and frequency-domain photoacoustic imaging by a fingertip laser diode system
	Zhong, Hongtao1,2,3 ; Zhang, Jiayao 1; Duan, Tingyang1,2,3 ; Lan, Hengrong1,2,3 ; Zhou, Meng1,3,4 ; Gao, Fei1
	2019-04-15
发表期刊	OPTICS LETTERS (IF:3.1[JCR-2023],3.1[5-Year])
ISSN	0146-9592
卷号	44 期号:8 页码:1988-1991
发表状态	已发表
DOI	10.1364/OL.44.001988
摘要	Photoacoustic imaging has attracted increasing research interest in recent years, due to its unique merit of combining light and sound. Enabling deep tissue imaging with high ultrasound spatial resolution and optical absorption contrast, photoacoustic imaging has been applied in various application scenarios including anatomical, functional and molecular imaging. However, the bulky and expensive laser source is one of the key bottlenecks that needs to be addressed for further compact system development. A photoacoustic imaging system based on a low-cost laser diode (LD) is one of the promising solutions. In this paper, we report a custom-made fingertip laser diode system enabling both pulsed and continuous modulation modes with shortest pulse-width of 40 ns, largest driving current of 13 A, and highest modulation frequency of 3 MHz, which is suitable for both time and frequency domain photoacoustic imaging. To the best of our knowledge, this may be the most compact laser source reported for photoacoustic imaging enabling both two modulation modes. Owing to its super-compact size, the proposed LD system could pave the pathway to a low-cost photoacoustic sensing and imaging device, even wearable photoacoustic biomedical sensors. (c) 2019 Optical Society of America
收录类别	SCI ; SCIE ; EI
语种	英语
资助项目	National Natural Science Foundation of China (NSFC)[61805139]
WOS研究方向	Optics
WOS类目	Optics
WOS记录号	WOS:000464601900027
出版者	OPTICAL SOC AMER
EI入藏号	20191806852163
EI主题词	Biosensors ; Costs ; Diodes ; Frequency domain analysis ; Light absorption ; Modulation ; Molecular imaging ; Photoacoustic effect
EI分类号	Light/Optics:741.1 ; Lasers, General:744.1 ; Imaging Techniques:746 ; Cost and Value Engineering; Industrial Economics:911 ; Mathematical Transformations:921.3
WOS关键词	LOW-COST
原始文献类型	Article
引用统计	正在获取...
文献类型	期刊论文
条目标识符	https://kms.shanghaitech.edu.cn/handle/2MSLDSTB/34338
专题	信息科学与技术学院_硕士生信息科学与技术学院_PI研究组_高飞组信息科学与技术学院_博士生
通讯作者	Gao, Fei
作者单位	1.ShanghaiTech Univ, Hybrid Imaging Syst Lab, Sch Informat Sci & Technol, Shanghai, Peoples R China 2.Chinese Acad Sci, Shanghai Inst Microsyst & Informat Technol, Shanghai 200050, Peoples R China 3.Univ Chinese Acad Sci, Beijing 100049, Peoples R China 4.Chinese Acad Sci, Shanghai Adv Res Inst, Shanghai 201210, Peoples R China
第一作者单位	上海科技大学
通讯作者单位	上海科技大学
第一作者的第一单位	上海科技大学
推荐引用方式 GB/T 7714	Zhong, Hongtao,Zhang, Jiayao,Duan, Tingyang,et al. Enabling both time-domain and frequency-domain photoacoustic imaging by a fingertip laser diode system[J]. OPTICS LETTERS,2019,44(8):1988-1991.
APA	Zhong, Hongtao,Zhang, Jiayao,Duan, Tingyang,Lan, Hengrong,Zhou, Meng,&Gao, Fei.(2019).Enabling both time-domain and frequency-domain photoacoustic imaging by a fingertip laser diode system.OPTICS LETTERS,44(8),1988-1991.
MLA	Zhong, Hongtao,et al."Enabling both time-domain and frequency-domain photoacoustic imaging by a fingertip laser diode system".OPTICS LETTERS 44.8(2019):1988-1991.