上海科技大学知识管理系统

本公开提供了式(I)化合物或其盐、对映异构体、立体异构体、溶剂化物或多晶型物及其应用，以及包含式(I)化合物或其盐、对映异构体、立体异构体、溶剂化物或多晶型物作为活性成分的药物组合物及其应用。 所述化合物可以有效地预防和//或治疗与TNF-α相关的疾病或病症。

The present disclosure provides compounds of formula (I) or salts, enantiomers, stereoisomers, solvates, or polymorphs thereof, and applications thereof, and pharmaceutical compositions comprising, as an active ingredient, the compound of Formula (I) or a salt, enantiomer, stereoisomer, solvate, or polymorph thereof, and applications of the pharmaceutical compositions. The compounds can effectively prevent and//or treat diseases or disorders associated with TNF-α.