Metabolism as a guiding force for immunity

doi:10.1038/s41556-018-0217-x

	Metabolism as a guiding force for immunity
	Jung, Jonathan 1,2; Zeng, Hu 3,4; Horng, Tiffany#1,5
	2019-01
发表期刊	NATURE CELL BIOLOGY (IF:17.3[JCR-2023],24.2[5-Year])
ISSN	1465-7392
卷号	21 期号:1 页码:85-93
发表状态	已发表
DOI	10.1038/s41556-018-0217-x
摘要	Recent studies indicate that cellular metabolism plays a key role in supporting immune cell maintenance and development. Here, we review how metabolism guides immune cell activation and differentiation to distinct cellular states, and how differential regulation of metabolism allows for context-dependent support during activation and lineage commitment. We discuss emerging principles of metabolic support of immune cell function in physiology and disease, as well as their general relevance to the field of cell biology.
收录类别	SCI ; SCIE
语种	英语
资助项目	NIH[R01AI102964]
WOS研究方向	Cell Biology
WOS类目	Cell Biology
WOS记录号	WOS:000454708400011
出版者	NATURE PUBLISHING GROUP
WOS关键词	T-CELL METABOLISM ; REGULATORY T ; SUCCINATE-DEHYDROGENASE ; MITOCHONDRIAL BIOGENESIS ; TUMOR MICROENVIRONMENT ; PERITONEAL-MACROPHAGES ; GENE-EXPRESSION ; T-HELPER-1 CELL ; DENDRITIC CELL ; NITRIC-OXIDE
原始文献类型	Review
引用统计	正在获取...
文献类型	期刊论文
条目标识符	https://kms.shanghaitech.edu.cn/handle/2MSLDSTB/30034
专题	生命科学与技术学院_PI研究组_洪诗雅组
通讯作者	Zeng, Hu; Horng, Tiffany#
作者单位	1.Harvard TH Chan Sch Publ Hlth, Dept Genet & Complex Dis, Boston, MA 02115 USA 2.Univ Glasgow, Sch Med, Glasgow, Lanark, Scotland 3.Mayo Clin, Div Rheumatol, Rochester, MN 55905 USA 4.Mayo Clin, Dept Immunol, Rochester, MN 55905 USA 5.ShanghaiTech Univ, Shanghai, Peoples R China
通讯作者单位	上海科技大学
推荐引用方式 GB/T 7714	Jung, Jonathan,Zeng, Hu,Horng, Tiffany#. Metabolism as a guiding force for immunity[J]. NATURE CELL BIOLOGY,2019,21(1):85-93.
APA	Jung, Jonathan,Zeng, Hu,&Horng, Tiffany#.(2019).Metabolism as a guiding force for immunity.NATURE CELL BIOLOGY,21(1),85-93.
MLA	Jung, Jonathan,et al."Metabolism as a guiding force for immunity".NATURE CELL BIOLOGY 21.1(2019):85-93.