A new imaging mode based on X-ray CT as prior image and sparsely sampled projections for rapid clinical proton CT

doi:10.1007/s41365-023-01280-6

	A new imaging mode based on X-ray CT as prior image and sparsely sampled projections for rapid clinical proton CT
	Yang, Yu-Qing1,2,3,4 ; Fang, Wen-Cheng 2,4,5; Huang, Xiao-Xia 4; Du, Qiang 6; Li, Ming 6; Zheng, Jian 6; Zhao, Zhen-Tang2,3,4,5
	2023
发表期刊	NUCLEAR SCIENCE AND TECHNOLOGY (IF:3.6[JCR-2023],2.4[5-Year])
ISSN	1001-8042
EISSN	2210-3147
卷号	34 期号:8
发表状态	已发表
DOI	10.1007/s41365-023-01280-6
摘要	Proton computed tomography (CT) has a distinct practical significance in clinical applications. It eliminates 3-5% errors caused by the transformation of Hounsfield unit (HU) to relative stopping power (RSP) values when using X-ray CT for positioning and treatment planning systems (TPSs). Following the development of FLASH proton therapy, there are increased requirements for accurate and rapid positioning in TPSs. Thus, a new rapid proton CT imaging mode is proposed based on sparsely sampled projections. The proton beam was boosted to 350 MeV by a compact proton linear accelerator (LINAC). In this study, the comparisons of the proton scattering with the energy of 350 MeV and 230 MeV are conducted based on GEANT4 simulations. As the sparsely sampled information associated with beam acquisitions at 12 angles is not enough for reconstruction, X-ray CT is used as a prior image. The RSP map generated by converting the X-ray CT was constructed based on Monte Carlo simulations. Considering the estimation of the most likely path (MLP), the prior image-constrained compressed sensing (PICCS) algorithm is used to reconstruct images from two different phantoms using sparse proton projections of 350 MeV parallel proton beam. The results show that it is feasible to realize the proton image reconstruction with the rapid proton CT imaging proposed in this paper. It can produce RSP maps with much higher accuracy for TPSs and fast positioning to achieve ultra-fast imaging for real-time image-guided radiotherapy (IGRT) in clinical proton therapy applications.
关键词	Proton CT Real-time image guidance Image reconstruction Proton therapy
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收录类别	SCI ; EI
语种	英语
资助项目	Research collaboration on Thailand's new synchrotron light source facility (SPS-II)[ANSO-CR-KP-2020-16]
WOS研究方向	Nuclear Science & Technology ; Physics
WOS类目	Nuclear Science & Technology ; Physics, Nuclear
WOS记录号	WOS:001057478700001
出版者	SPRINGER SINGAPORE PTE LTD
EI入藏号	20233514641844
EI主题词	Image reconstruction
EI分类号	723.4 Artificial Intelligence ; 723.5 Computer Applications ; 922.2 Mathematical Statistics ; 932.1.1 Particle Accelerators
原始文献类型	Journal article (JA)
引用统计	正在获取...
文献类型	期刊论文
条目标识符	https://kms.shanghaitech.edu.cn/handle/2MSLDSTB/295965
专题	物质科学与技术学院物质科学与技术学院_特聘教授组_赵振堂组物质科学与技术学院_博士生
通讯作者	Fang, Wen-Cheng; Du, Qiang
作者单位	1.Chinese Acad Sci, Shanghai Inst Appl Phys, Shanghai 201800, Peoples R China 2.Univ Chinese Acad Sci, Beijing 100049, Peoples R China 3.ShanghaiTech Univ, Sch Phys Sci & Technol, Shanghai 201210, Peoples R China 4.Chinese Acad Sci, Shanghai Adv Res Inst, Shanghai Synchrotron Radiat Facil, Shanghai 201204, Peoples R China 5.Shanghai Key Lab Cryogen & Superconducting RF Tech, Shanghai, Peoples R China 6.Chinese Acad Sci, Suzhou Inst Biomed Engn & Technol, Suzhou, Peoples R China
第一作者单位	物质科学与技术学院
推荐引用方式 GB/T 7714	Yang, Yu-Qing,Fang, Wen-Cheng,Huang, Xiao-Xia,et al. A new imaging mode based on X-ray CT as prior image and sparsely sampled projections for rapid clinical proton CT[J]. NUCLEAR SCIENCE AND TECHNOLOGY,2023,34(8).
APA	Yang, Yu-Qing.,Fang, Wen-Cheng.,Huang, Xiao-Xia.,Du, Qiang.,Li, Ming.,...&Zhao, Zhen-Tang.(2023).A new imaging mode based on X-ray CT as prior image and sparsely sampled projections for rapid clinical proton CT.NUCLEAR SCIENCE AND TECHNOLOGY,34(8).
MLA	Yang, Yu-Qing,et al."A new imaging mode based on X-ray CT as prior image and sparsely sampled projections for rapid clinical proton CT".NUCLEAR SCIENCE AND TECHNOLOGY 34.8(2023).

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