上海科技大学知识管理系统

本发明提供了式(I)化合物或其盐、对映体、立体异构体、溶剂化物和多晶型物及其应用，以及含有所述式(I)化合物或其盐、对映体、立体异构体、溶剂化物和多晶型物作为活性成分的药物组合物及其应用。 该化合物可以有效地预防和//或治疗与TNF-α相关的疾病或症状。

Provided are a compound of formula (I) or a salt, an enantiomer, a stereoisomer, a solvate, and a polymorph thereof and an application thereof, and a pharmaceutical composition containing the compound of formula (I) or the salt, the enantiomer, the stereoisomer, the solvate, and the polymorph thereof which are used as active ingredients, and an application of the pharmaceutical composition. The compound can effectively prevent and//or treat diseases or symptoms associated with TNF-α.