Neural and metabolic basis of dynamic resting state fMRI

doi:10.1016/j.neuroimage.2017.09.010

KMS > iHuman研究所 > PI研究组 > Garth John Thompson组

	Neural and metabolic basis of dynamic resting state fMRI
	Thompson, Garth J.
	2018-10-15
发表期刊	NEUROIMAGE
ISSN	1053-8119
卷号	180 页码:448-462
发表状态	已发表
DOI	10.1016/j.neuroimage.2017.09.010
摘要	Resting state fMRI (rsfMRI) as a technique showed much initial promise for use in psychiatric and neurological diseases where diagnosis and treatment were difficult. To realize this promise, many groups have moved towards examining "dynamic rsfMRI," which relies on the assumption that rsfMRI measurements on short time scales remain relevant to the underlying neural and metabolic activity. Many dynamic rsfMRI studies have demonstrated differences between clinical or behavioral groups beyond what static rsfMRI measured, suggesting a neurometabolic basis. Correlative studies combining dynamic rsfMRI and other physiological measurements have supported this. However, they also indicate multiple mechanisms and, if using correlation alone, it is difficult to separate cause and effect. Hypothesis-driven studies are needed, a few of which have begun to illuminate the underlying neurometabolic mechanisms that shape observed differences in dynamic rsfMRI. While the number of potential noise sources, potential actual neurometabolic sources, and methodological considerations can seem overwhelming, dynamic rsfMRI provides a rich opportunity in systems neuroscience. Even an incrementally better understanding of the neurometabolic basis of dynamic rsfMRI would expand rsfMRI's research and clinical utility, and the studies described herein take the first steps on that path forward.
收录类别	SCI ; SCIE
语种	英语
资助项目	NIH[2T32DA022975-06A1] ; NIH[P30 NS-052519]
WOS研究方向	Neurosciences & Neurology ; Radiology, Nuclear Medicine & Medical Imaging
WOS类目	Neurosciences ; Neuroimaging ; Radiology, Nuclear Medicine & Medical Imaging
WOS记录号	WOS:000443271100011
出版者	ACADEMIC PRESS INC ELSEVIER SCIENCE
WOS关键词	DEFAULT-MODE NETWORK ; BOLD FUNCTIONAL CONNECTIVITY ; BRAIN ACTIVITY FLUCTUATIONS ; LOW-FREQUENCY FLUCTUATIONS ; TIME-VARYING CONNECTIVITY ; HEART-RATE-VARIABILITY ; CEREBRAL-BLOOD-FLOW ; GLOBAL SIGNAL ; SPATIOTEMPORAL DYNAMICS ; SCHIZOPHRENIA-PATIENTS
原始文献类型	Review
引用统计
文献类型	期刊论文
条目标识符	https://kms.shanghaitech.edu.cn/handle/2MSLDSTB/27689
专题	iHuman研究所_PI研究组_Garth John Thompson组
通讯作者	Thompson, Garth J.
作者单位	ShanghaiTech Univ, iHuman Inst, Shanghai 201210, Peoples R China
第一作者单位	iHuman研究所
通讯作者单位	iHuman研究所
第一作者的第一单位	iHuman研究所
推荐引用方式 GB/T 7714	Thompson, Garth J.. Neural and metabolic basis of dynamic resting state fMRI[J]. NEUROIMAGE,2018,180:448-462.
APA	Thompson, Garth J..(2018).Neural and metabolic basis of dynamic resting state fMRI.NEUROIMAGE,180,448-462.
MLA	Thompson, Garth J.."Neural and metabolic basis of dynamic resting state fMRI".NEUROIMAGE 180(2018):448-462.