Selectivity and Cooperativity in the Binding of Multiple Guests to a Pillar[5]arene-Crown Ether Fused Tricyclic Host

doi:10.1021/acs.joc.5b01038

	Selectivity and Cooperativity in the Binding of Multiple Guests to a Pillar[5]arene-Crown Ether Fused Tricyclic Host
	Hu, Wei-Bo 1,2; Xie, Chang-Dong 3; Hu, Wen-Jing 1; Zhao, Xiao-Li 4,5; Liu, Yahu A.6; Huo, Ji-Chuan 3; Li, Jiu-Sheng 1; Jiang, Biao 1; Wen, Ke1,3,7
	2015-08-21
发表期刊	JOURNAL OF ORGANIC CHEMISTRY (IF:3.3[JCR-2023],3.2[5-Year])
ISSN	0022-3263
卷号	80 期号:16 页码:7994-8000
发表状态	已发表
DOI	10.1021/acs.joc.5b01038
摘要	A novel tricylic host molecule 1 that consists of two pillar[S]arene units and a crown ether ring was found to selectively bind two kinds of guest molecules with different shapes, sizes, and electronic constitutions, namely 1,4-dicyanobutane G1 and paraquat G2, with its two macrocyclic subunits, to form a four-component complex 2G1 subset of 1 superset of G2. An H-1 NMR study of stepwise bindings of G1 and G2 to host 1 in CDCl3/DMSO-d(6) revealed that the strength of the association between complex 2G1 subset of 1 and guest G2 was only one-fourth of that between free 1 and G2, demonstrating a negative heterotropic cooperativity of G1 in the binding of G2 to host 1.
收录类别	SCI ; IC ; EI
语种	英语
资助项目	Chinese Academy of Sciences[XDA01020304]
WOS研究方向	Chemistry
WOS类目	Chemistry, Organic
WOS记录号	WOS:000360103000016
出版者	AMER CHEMICAL SOC
EI入藏号	20153501207918
EI主题词	Ethers ; Ligands ; Molecules
EI分类号	Physical Chemistry:801.4 ; Organic Compounds:804.1 ; Atomic and Molecular Physics:931.3
WOS关键词	TOBACCO-MOSAIC-VIRUS ; MOLECULAR RECOGNITION ; NOBEL LECTURE ; PARAQUAT ; COMPLEXATION ; HEMOGLOBIN ; PORPHYRIN ; PROTEIN ; DERIVATIVES ; PILLARENES
原始文献类型	Article
引用统计	正在获取...
文献类型	期刊论文
条目标识符	https://kms.shanghaitech.edu.cn/handle/2MSLDSTB/2154
专题	物质科学与技术学院_特聘教授组_文珂组
通讯作者	Huo, Ji-Chuan
作者单位	1.Chinese Acad Sci, Shanghai Adv Res Inst, Shanghai 201210, Peoples R China 2.Univ Chinese Acad Sci, Beijing 100039, Peoples R China 3.Southwest Univ Sci & Technol, Sch Mat Sci & Engn, Mianyang 621010, Sichuan, Peoples R China 4.E China Normal Univ, Shanghai Key Lab Green Chem & Chem Proc, Shanghai 200062, Peoples R China 5.E China Normal Univ, Dept Chem, Shanghai 200062, Peoples R China 6.ChemBridge Res Labs Inc, Med Chem, San Diego, CA 92127 USA 7.ShanghaiTech Univ, Sch Phys Sci & Technol, Shanghai 201210, Peoples R China
推荐引用方式 GB/T 7714	Hu, Wei-Bo,Xie, Chang-Dong,Hu, Wen-Jing,et al. Selectivity and Cooperativity in the Binding of Multiple Guests to a Pillar[5]arene-Crown Ether Fused Tricyclic Host[J]. JOURNAL OF ORGANIC CHEMISTRY,2015,80(16):7994-8000.
APA	Hu, Wei-Bo.,Xie, Chang-Dong.,Hu, Wen-Jing.,Zhao, Xiao-Li.,Liu, Yahu A..,...&Wen, Ke.(2015).Selectivity and Cooperativity in the Binding of Multiple Guests to a Pillar[5]arene-Crown Ether Fused Tricyclic Host.JOURNAL OF ORGANIC CHEMISTRY,80(16),7994-8000.
MLA	Hu, Wei-Bo,et al."Selectivity and Cooperativity in the Binding of Multiple Guests to a Pillar[5]arene-Crown Ether Fused Tricyclic Host".JOURNAL OF ORGANIC CHEMISTRY 80.16(2015):7994-8000.