A genetic module at one locus in rice protects chloroplasts to enhance thermotolerance

doi:10.1126/science.abo5721

	A genetic module at one locus in rice protects chloroplasts to enhance thermotolerance
	Zhang, Hai1,2,3,4 ; Zhou, Ji-Fu 1,3; Kan, Yi 1,2; Shan, Jun-Xiang 1,2; Ye, Wang-Wei 1,2; Dong, Nai-Qian 1,2; Guo, Tao 1; Xiang, You-Huang 1,2,3; Yang, Yi-Bing 1,2,3; Li, Ya-Chao1,3,4 ; Zhao, Huai-Yu 1,3; Yu, Hong-Xiao 1,3; Lu, Zi-Qi1,4 ; Guo, Shuang-Qin 1,2,3; Lei, Jie-Jie 1,2,3; Liao, Ben1,4 ; Mu, Xiao-Rui 1,2,3; Cao, Ying-Jie 1,2,3; Yu, Jia-Jun1,4 ; Lin, Youshun 5; Lin, Hong-Xuan1,2,3,4
	2022-06-17
发表期刊	SCIENCE (IF:44.7[JCR-2023],50.3[5-Year])
ISSN	0036-8075
EISSN	1095-9203
卷号	376 期号:6599
发表状态	已发表
DOI	10.1126/science.abo5721
摘要	How the plasma membrane senses external heat-stress signals to communicate with chloroplasts to orchestrate thermotolerance remains elusive. We identified a quantitative trait locus, Thermo-tolerance 3 (TT3), consisting of two genes, TT3.1 and TT3.2, that interact together to enhance rice thermotolerance and reduce grain-yield losses caused by heat stress. Upon heat stress, plasma membrane-localized E3 ligase TT3.1 translocates to the endosomes, on which TT3.1 ubiquitinates chloroplast precursor protein TT3.2 for vacuolar degradation, implying that TT3.1 might serve as a potential thermosensor. Lesser accumulated, mature TT3.2 proteins in chloroplasts are essential for protecting thylakoids from heat stress. Our findings not only reveal a TT3.1-TT3.2 genetic module at one locus that transduces heat signals from plasma membrane to chloroplasts but also provide the strategy for breeding highly thermotolerant crops.
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收录类别	SCI ; SCIE
语种	英语
资助项目	National Natural Science Foundation of China["31788103","31630052"] ; Chinese Academy of Sciences["XDB27010104","QYZDY-SSW-SMC023","159231KYSB20200008"] ; Laboratory of Lingnan Modern Agriculture Project[NT2021002] ; Shanghai Jiao Tong University[ZXWH3150101/006]
WOS研究方向	Science & Technology - Other Topics
WOS类目	Multidisciplinary Sciences
WOS记录号	WOS:000815052900040
出版者	AMER ASSOC ADVANCEMENT SCIENCE
引用统计	正在获取...
文献类型	期刊论文
条目标识符	https://kms.shanghaitech.edu.cn/handle/2MSLDSTB/214807
专题	生命科学与技术学院_博士生生命科学与技术学院_特聘教授组_林鸿宣组生命科学与技术学院_硕士生
通讯作者	Lin, Youshun; Lin, Hong-Xuan
作者单位	1.Chinese Acad Sci, CAS Ctr Excellence Mol Plant Sci, Shanghai Inst Plant Physiol & Ecol, Natl Key Lab Plant Mol Genet, Shanghai 200032, Peoples R China 2.Guangdong Lab Lingnan Modern Agr, Guangzhou 510642, Peoples R China 3.Univ Chinese Acad Sci, Beijing 100049, Peoples R China 4.ShanghaiTech Univ, Sch Life Sci & Technol, Shanghai 201210, Peoples R China 5.Shanghai Jiao Tong Univ, Joint Ctr Single Cell Biol, Sch Agr & Biol, Shanghai 200240, Peoples R China
第一作者单位	生命科学与技术学院
通讯作者单位	生命科学与技术学院
推荐引用方式 GB/T 7714	Zhang, Hai,Zhou, Ji-Fu,Kan, Yi,et al. A genetic module at one locus in rice protects chloroplasts to enhance thermotolerance[J]. SCIENCE,2022,376(6599).
APA	Zhang, Hai.,Zhou, Ji-Fu.,Kan, Yi.,Shan, Jun-Xiang.,Ye, Wang-Wei.,...&Lin, Hong-Xuan.(2022).A genetic module at one locus in rice protects chloroplasts to enhance thermotolerance.SCIENCE,376(6599).
MLA	Zhang, Hai,et al."A genetic module at one locus in rice protects chloroplasts to enhance thermotolerance".SCIENCE 376.6599(2022).