Squamous Transition of Lung Adenocarcinoma and Drug Resistance

doi:10.1016/j.trecan.2016.08.002

	Squamous Transition of Lung Adenocarcinoma and Drug Resistance
	Hou, Shenda 1,2,3; Han, Xiangkun 1,2,3; Ji, Hongbin1,2,3,4
	2016-09
发表期刊	TRENDS IN CANCER (IF:14.3[JCR-2023],17.1[5-Year])
ISSN	2405-8025
卷号	2 期号:9 页码:463-466
发表状态	已发表
DOI	10.1016/j.trecan.2016.08.002
摘要	Studies in mouse models support an essential role of lung adenocarcinoma (ADC) to squamous cell carcinoma (SCC) transition (AST) in the development of drug resistance. Recent observations in the clinic further suggest that this type of histological transition may be responsible for resistance to tyrosine kinase inhibitor (TKI) therapy and chemotherapy in relapsed EGFR-mutant lung ADC patients. Here we summarize the current understanding of AST and drug resistance.
收录类别	SCI
语种	英语
资助项目	Science and Technology Commission of Shanghai Municipality[15XD1504000]
WOS研究方向	Oncology
WOS类目	Oncology
WOS记录号	WOS:000432225600002
出版者	CELL PRESS
原始文献类型	Editorial Material
引用统计	正在获取...
文献类型	期刊论文
条目标识符	https://kms.shanghaitech.edu.cn/handle/2MSLDSTB/20879
专题	生命科学与技术学院_特聘教授组_季红斌组
通讯作者	Ji, Hongbin
作者单位	1.Chinese Acad Sci, Shanghai Inst Biol Sci, Inst Biochem & Cell Biol, Key Lab Syst Biol, Shanghai 200031, Peoples R China 2.Chinese Acad Sci, Shanghai Inst Biol Sci, Inst Biochem & Cell Biol, CAS Ctr Excellence Mol Cell Sci, Shanghai 200031, Peoples R China 3.Chinese Acad Sci, Shanghai Inst Biol Sci, Inst Biochem & Cell Biol, Innovat Ctr Cell Signaling Network, Shanghai 200031, Peoples R China 4.Shanghai Tech Univ, Sch Life Sci & Technol, Shanghai 200120, Peoples R China
通讯作者单位	生命科学与技术学院
推荐引用方式 GB/T 7714	Hou, Shenda,Han, Xiangkun,Ji, Hongbin. Squamous Transition of Lung Adenocarcinoma and Drug Resistance[J]. TRENDS IN CANCER,2016,2(9):463-466.
APA	Hou, Shenda,Han, Xiangkun,&Ji, Hongbin.(2016).Squamous Transition of Lung Adenocarcinoma and Drug Resistance.TRENDS IN CANCER,2(9),463-466.
MLA	Hou, Shenda,et al."Squamous Transition of Lung Adenocarcinoma and Drug Resistance".TRENDS IN CANCER 2.9(2016):463-466.