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CRISPR-AsCas12f1 couples out-of-protospacer DNA unwinding with exonuclease activity in the sequential target cleavage 期刊论文
NUCLEIC ACIDS RESEARCH, 2024
作者:  Song, Xiaoxuan;  Chen, Ziting;  Sun, Wenjun;  Yang, Hao;  Guo, Lijuan
Adobe PDF(2215Kb)  |  收藏  |  浏览/下载：92/2  |  提交时间：2024/10/31
Inhibitor Development for α‑Synuclein Fibril's Disordered Region to Alleviate Parkinson's Disease Pathology 期刊论文
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2024, 卷号: 146
作者:  Zhang, Shenqing;  Xiang, Huaijiang;  Tao, Youqi;  Li, Juan;  Zeng, Shuyi
Adobe PDF(12245Kb)  |  收藏  |  浏览/下载：119/8  |  提交时间：2024/09/27
Dynamic phosphorylation of FOXA1 by Aurora B guides post-mitotic gene reactivation 期刊论文
CELL REPORTS, 2024, 卷号: 43, 期号: 114739
作者:  Zhang, Ting;  Liu, Shuaiyu;  Durojaye, Olanrewaju;  Xiong, Fangyuan;  Fang, Zhiyou
Adobe PDF(5903Kb)  |  收藏  |  浏览/下载：115/12  |  提交时间：2024/09/19
α-Synuclein amyloid fibril directly binds to LC3B and suppresses SQSTM1/p62-mediated selective autophagy 期刊论文
CELL RESEARCH, 2024, 卷号: 34
作者:  Xu, Qianhui;  Wang, Huilan;  Yang, Ruonan;  Tao, Youqi;  Wang, Ziying
Adobe PDF(1476Kb)  |  收藏  |  浏览/下载：115/12  |  提交时间：2024/09/19
RPA transforms RNase H1 to a bidirectional exonuclease for efficient RNA–DNA hybrid cleavage 期刊论文
NATURE COMMUNICATIONS, 2024, 卷号: 15, 期号: 1, 页码: 7464
作者:  Li, Yanan;  Liu, Chao;  Jia, Xinshuo;  Bi, Lulu;  Ren, Zhiyun
Adobe PDF(4386Kb)  |  收藏  |  浏览/下载：141/12  |  提交时间：2024/08/29
Binding adaptability of chemical ligands to polymorphic α-synuclein amyloid fibrils 期刊论文
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2024, 卷号: 121, 期号: 35, 页码: e2321633121
作者:  Liu, Kaien;  Tao, Youqi;  Zhao, Qiuyue;  Xia, Wencheng;  Li, Xiang
Adobe PDF(12416Kb)  |  收藏  |  浏览/下载：116/5  |  提交时间：2024/08/26
Phase-separated ParB enforces diverse DNA compaction modes and stabilizes the parS-centered partition complex 期刊论文
NUCLEIC ACIDS RESEARCH, 2024, 卷号: 52, 页码: 8385-8398
作者:  Zhao, Yilin;  Guo, Lijuan;  Hu, Jiaojiao;  Ren, Zhiyun;  Li, Yanan
Adobe PDF(2133Kb)  |  收藏  |  浏览/下载：201/44  |  提交时间：2024/06/24
A Tau PET tracer PBB3 binds to TMEM106B amyloid fibril in brain 期刊论文
CELL DISCOVERY, 2024, 卷号: 10, 期号: 1
作者:  Zhao, Qinyue;  Fan, Yun;  Zhao, Wanbing;  Ni, You;  Tao, Youqi
Adobe PDF(4431Kb)  |  收藏  |  浏览/下载：154/18  |  提交时间：2024/05/27
Single-molecule assay guided crRNA optimization enhances specific microRNA detection by CRISPR-Cas12a 期刊论文
SENSORS AND ACTUATORS B: CHEMICAL, 2024, 卷号: 406, 页码: 135389
作者:  Chen, Kaizhao;  Sun, Wenjun;  Zhong, Mingtian;  Xie, Jiaqi;  Huo, Yongkun
Adobe PDF(5066Kb)  |  收藏  |  浏览/下载：209/17  |  提交时间：2024/05/28
Cryo-EM structures reveal variant Tau amyloid fibrils between the rTg4510 mouse model and sporadic human tauopathies 期刊论文
CELL DISCOVERY, 2024, 卷号: 10, 期号: 1
作者:  Zhao, Wanbing;  Liu, Kaien;  Fan, Yun;  Zhao, Qinyue;  Tao, Youqi
Adobe PDF(2571Kb)  |  收藏  |  浏览/下载：162/27  |  提交时间：2024/05/28