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Benchmarking copy number aberrations inference tools using single-cell multi-omics datasets 预印本
2025
Authors:  Song, Minfang;  Ma, Shuai;  Wang, Gong;  Wang, Yukun;  Yang, Zhenzhen
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An upgraded nuclease prime editor platform enables high-efficiency singled or multiplexed knock-in/knockout of genes in mouse and sheep zygotes 期刊论文
PROTEIN & CELL, 2025
Authors:  Mao, Weijia;  Wang, Pei;  Zhou, Lei;  Li, Dongxu;  Li, Xiangyang
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Perillaldehyde Improves Parkinson-Like Deficits by Targeting G3BP Mediated Stress Granule Assembly in Preclinical Models 期刊论文
ADVANCED SCIENCE, 2025
Authors:  Fang, Minglv;  Luo, Lingling;  Chen, Youjia;  Liu, Ying;  Yan, Yingxuan
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Unveiling the Evolution of Antimicrobial Peptides in Gut Microbes via Foundation Model-Powered Framework 预印本
2025
Authors:  Li, Wenhui;  Huang, Baicheng;  Guo, Menghao;  Zeng, Zihan;  Cai, Tao
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Developing safe and efficient CGBE editor based on Cas-embedding strategy 期刊论文
SYNTHETIC AND SYSTEMS BIOTECHNOLOGY, 2025, 卷号: 10, 期号: 2
Authors:  Lin, Tian;  Wang, Xin;  Zhang, Yu;  Li, Guanglei;  Huang, Xingxu
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Viral N protein hijacks deaminase-containing RNA granules to enhance SARS-CoV-2 mutagenesis 期刊论文
EMBO JOURNAL, 2024, 卷号: 43, 期号: 24
Authors:  Li, Zhean
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Epigenetic editing alleviates Angelman syndrome phenotype in mice by unsilencing paternal Ube3a 期刊论文
CELL DISCOVERY, 2024, 卷号: 10, 期号: 1
Authors:  Liu, Yajing;  Lou, Sensen;  Li, Jinhui;  Liu, Yuanhua;  Huang, Shisheng
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Epigenomic landscapes during prefrontal cortex development and aging in rhesus 期刊论文
NATIONAL SCIENCE REVIEW, 2024, 卷号: 11, 期号: 8
Authors:  Ning, Chao;  Wu, Xi;  Zhao, Xudong;  Lu, Zongyang;  Yao, Xuelong
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用于提高碱基编辑精度的融合蛋白 专利
申请号:CN202410663572.1，申请日期: 2024-08-02，类型:发明申请，状态:实质审查
Inventors:  陈佳;  黄行许;  杨力;  杨贝;  李潇飒
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Zero-shot prediction of mutation effects with multimodal deep representation learning guides protein engineering 期刊论文
CELL RESEARCH, 2024
Authors:  Cheng, Peng;  Mao, Cong;  Tang, Jin;  Yang, Sen;  Cheng, Yu
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