Efficient synthesis of chiral biaryls via asymmetric Suzuki-Miyaura cross-coupling of ortho-bromo aryl triflates

doi:10.1016/j.tet.2015.12.051

	Efficient synthesis of chiral biaryls via asymmetric Suzuki-Miyaura cross-coupling of ortho-bromo aryl triflates
	Yang, Xintong1,2 ; Xu, Guangqing 2; Tang, Wenjun1,2
	2016-08-25
发表期刊	TETRAHEDRON (IF:2.1[JCR-2023],1.8[5-Year])
ISSN	0040-4020
卷号	72 期号:34 页码:5178-5183
发表状态	已发表
DOI	10.1016/j.tet.2015.12.051
摘要	Efficient asymmetric Suzuki-Miyaura coupling of ortho-bromo aryl triflates with various arylboronic acids were described, providing a series of chiral biaryl triflates in high yields and up to 91% ee under mild conditions. The aryl triflates could be easily transformed to various chiral biaryl products by further derivatization. A one-pot tandem asymmetric cross-coupling/cross-coupling sequence was also achieved by using a single palladium catalyst, demonstrating the versatility of this method for preparation of chiral biaryl products. (C) 2015 Elsevier Ltd. All rights reserved.
关键词	Suzuki-Miyaura cross-coupling Biaryl triflate High enantioselectivity Polar-pi secondary interaction One-pot tandem cross-coupling
收录类别	SCI ; IC
语种	英语
WOS研究方向	Chemistry
WOS类目	Chemistry, Organic
WOS记录号	WOS:000381592100005
出版者	PERGAMON-ELSEVIER SCIENCE LTD
WOS关键词	ENANTIOSELECTIVE SYNTHESIS ; NATURAL-PRODUCTS ; LIGANDS ; BINOL
原始文献类型	Article
引用统计	正在获取...
文献类型	期刊论文
条目标识符	https://kms.shanghaitech.edu.cn/handle/2MSLDSTB/1748
专题	物质科学与技术学院物质科学与技术学院_特聘教授组_汤文军组物质科学与技术学院_硕士生
通讯作者	Tang, Wenjun
作者单位	1.ShanghaiTech Univ, Sch Phys Sci & Technol, Shanghai 200031, Peoples R China 2.Chinese Acad Sci, Shanghai Inst Organ Chem, State Key Lab Bioorgan & Nat Prod Chem, Shanghai 200032, Peoples R China
第一作者单位	物质科学与技术学院
通讯作者单位	物质科学与技术学院
第一作者的第一单位	物质科学与技术学院
推荐引用方式 GB/T 7714	Yang, Xintong,Xu, Guangqing,Tang, Wenjun. Efficient synthesis of chiral biaryls via asymmetric Suzuki-Miyaura cross-coupling of ortho-bromo aryl triflates[J]. TETRAHEDRON,2016,72(34):5178-5183.
APA	Yang, Xintong,Xu, Guangqing,&Tang, Wenjun.(2016).Efficient synthesis of chiral biaryls via asymmetric Suzuki-Miyaura cross-coupling of ortho-bromo aryl triflates.TETRAHEDRON,72(34),5178-5183.
MLA	Yang, Xintong,et al."Efficient synthesis of chiral biaryls via asymmetric Suzuki-Miyaura cross-coupling of ortho-bromo aryl triflates".TETRAHEDRON 72.34(2016):5178-5183.