PEG-induced orientation enhancement of supported lipid multi-bilayers revealed by surface X-ray diffraction

doi:10.1016/j.surfin.2022.101762

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	PEG-induced orientation enhancement of supported lipid multi-bilayers revealed by surface X-ray diffraction
	Xu, Yihui1 ; Xie, Qing 2; Fan, Jiadong1 ; Gu, Yueliang 2; Li, Xiaolong 2; Liu, Zhi1 ; Jiang, Huaidong1
	2022-04
发表期刊	SURFACES AND INTERFACES (IF:5.7[JCR-2023],5.8[5-Year])
ISSN	2468-0230
卷号	29
发表状态	已发表
DOI	10.1016/j.surfin.2022.101762
摘要	Polyethylene glycol (PEG) is one of the most widely used polymers in cosmetic and biomedical products. The supported lipid multi-bilayer (SLMB) is an important model membrane, which is highly advantageous to surface diffraction techniques. In this study, in-situ grazing-incidence X-ray diffraction, X-ray reflectivity, and X-ray rocking scans are combined to systematically study the effects of PEG on SLMBs. A structure restoring effect of PEG is revealed, which is indicated by the reduced bilayer periodicity, improved molecular packing, and enhanced membrane orientation of the SLMBs. Moreover, this effect is found to be irreversible; i.e., removing PEG does not eliminate this effect. This finding may contribute to a better understanding of PEG-membrane interaction and the further biomedical applications of PEG.
关键词	Enhancement Lipid multi-bilayer Membrane orientation PEG X-ray diffraction
URL	查看原文
收录类别	SCI ; SCIE
语种	英语
资助项目	Strategic Priority Research Program of Chinese Academy of Sciences[XDB 37040303] ; Major State Basic Research Development Program of China[2017YFA0504802] ; National Natural Science Foundation of China[21727817]
WOS研究方向	Chemistry ; Materials Science ; Physics
WOS类目	Chemistry, Physical ; Materials Science, Coatings & Films ; Physics, Applied ; Physics, Condensed Matter
WOS记录号	WOS:000764896100001
出版者	ELSEVIER
Scopus 记录号	2-s2.0-85123386075
来源库	Scopus
引用统计	正在获取...
文献类型	期刊论文
条目标识符	https://kms.shanghaitech.edu.cn/handle/2MSLDSTB/153586
专题	大科学中心大科学中心_PI研究组_刘志组大科学中心_PI研究组_江怀东组大科学中心_公共科研平台_大科学装置建设部
通讯作者	Xu, Yihui; Jiang, Huaidong
作者单位	1.ShanghaiTech Univ, Ctr Transformat Sci, 393 Middle Huaxia Rd, Shanghai 201210, Peoples R China 2.Chinese Acad Sci, Shanghai Adv Res Inst, 99 Haike Rd, Shanghai 201210, Peoples R China
第一作者单位	上海科技大学
通讯作者单位	上海科技大学
第一作者的第一单位	上海科技大学
推荐引用方式 GB/T 7714	Xu, Yihui,Xie, Qing,Fan, Jiadong,et al. PEG-induced orientation enhancement of supported lipid multi-bilayers revealed by surface X-ray diffraction[J]. SURFACES AND INTERFACES,2022,29.
APA	Xu, Yihui.,Xie, Qing.,Fan, Jiadong.,Gu, Yueliang.,Li, Xiaolong.,...&Jiang, Huaidong.(2022).PEG-induced orientation enhancement of supported lipid multi-bilayers revealed by surface X-ray diffraction.SURFACES AND INTERFACES,29.
MLA	Xu, Yihui,et al."PEG-induced orientation enhancement of supported lipid multi-bilayers revealed by surface X-ray diffraction".SURFACES AND INTERFACES 29(2022).