Neural circuit control of innate behaviors

doi:10.1007/s11427-021-2043-2

	Neural circuit control of innate behaviors
	Xiao, Wei 1,2; Jiao, Zhuo-Lei 3; Senol, Esra 4; Yao, Jiwei 5; Zhao, Miao 6; Zhao, Zheng-Dong 7; Chen, Xiaowei 8,9,10; Cao, Peng 6; Fu, Yu 4; Gao, Zhihua 1,2; Shen, Wei L.11 ; Xu, Xiao-Hong 3
	2021-12-01
发表期刊	SCIENCE CHINA-LIFE SCIENCES (IF:8.0[JCR-2023],7.3[5-Year])
ISSN	1674-7305
EISSN	1869-1889
发表状态	已发表
DOI	10.1007/s11427-021-2043-2
摘要	All animals possess a plethora of innate behaviors that do not require extensive learning and are fundamental for their survival and propagation. With the advent of newly-developed techniques such as viral tracing and optogenetic and chemogenetic tools, recent studies are gradually unraveling neural circuits underlying different innate behaviors. Here, we summarize current development in our understanding of the neural circuits controlling predation, feeding, male-typical mating, and urination, highlighting the role of genetically defined neurons and their connections in sensory triggering, sensory to motor/motivation transformation, motor/motivation encoding during these different behaviors. Along the way, we discuss possible mechanisms underlying binge-eating disorder and the pro-social effects of the neuropeptide oxytocin, elucidating the clinical relevance of studying neural circuits underlying essential innate functions. Finally, we discuss some exciting brain structures recurrently appearing in the regulation of different behaviors, which suggests both divergence and convergence in the neural encoding of specific innate behaviors. Going forward, we emphasize the importance of multi-angle and cross-species dissections in delineating neural circuits that control innate behaviors.
关键词	innate behavior neural circuit feeding social behavior urination
URL	查看原文
收录类别	SCI ; SCIE
语种	英语
资助项目	National Key Research and Development Program of China[2017YFA0104200] ; National Natural Science Foundation of China[31871066,31922028,31900721,32122039] ; Shanghai Municipal Science and Technology Major Project[2018SHZDZX05] ; Strategic Priority Research Program of the Chinese Academy of Sciences[XDB32000000] ; Shanghai Science and Technology Committee of Shanghai City[19140903800,"21XD1422700"]
WOS研究方向	Life Sciences & Biomedicine - Other Topics
WOS类目	Biology
WOS记录号	WOS:000739263300001
出版者	SCIENCE PRESS
引用统计	正在获取...
文献类型	期刊论文
条目标识符	https://kms.shanghaitech.edu.cn/handle/2MSLDSTB/148752
专题	生命科学与技术学院_PI研究组_沈伟组
通讯作者	Chen, Xiaowei; Cao, Peng; Fu, Yu; Gao, Zhihua; Shen, Wei L.; Xu, Xiao-Hong
作者单位	1.Zhejiang Univ, Sch Brain Sci & Brain Med, NHC & CAMS Key Lab Med Neurobiol, Affiliated Hosp 2,Dept Neurobiol, Hangzhou 310058, Peoples R China 2.Zhejiang Univ, Sch Brain Sci & Brain Med, NHC & CAMS Key Lab Med Neurobiol, Affiliated Hosp 2,Dept Neurol, Hangzhou 310058, Peoples R China 3.Chinese Acad Sci, Shanghai Ctr Brain Sci & Brain Inspired Intellige, CAS Ctr Excellence Brain Sci & Intelligence Techn, Inst Neurosci,State Key Lab Neurosci, Shanghai 200031, Peoples R China 4.ASTAR, Inst Mol & Cell Biol, Singapore 138667, Singapore 5.Chongqing Univ, Sch Med, Ctr Neurointelligence, Chongqing 400030, Peoples R China 6.Tsinghua Univ, Tsinghua Inst Multidisciplinary Biomed Res, Natl Inst Biol Sci, Beijing 100084, Peoples R China 7.Harvard Med Sch, Boston Childrens Hosp, Boston, MA 02115 USA 8.Third Mil Med Univ, Brain Res Ctr, Chongqing 400038, Peoples R China 9.Third Mil Med Univ, State Key Lab Trauma Burns & Combined Injury, Chongqing 400038, Peoples R China 10.Chinese Acad Sci, Shanghai Inst Biol Sci, CAS Ctr Excellence Brain Sci & Intelligence Techn, Shanghai 200031, Peoples R China 11.ShanghaiTech Univ, Sch Life Sci & Technol, Shanghai 201210, Peoples R China
通讯作者单位	生命科学与技术学院
推荐引用方式 GB/T 7714	Xiao, Wei,Jiao, Zhuo-Lei,Senol, Esra,et al. Neural circuit control of innate behaviors[J]. SCIENCE CHINA-LIFE SCIENCES,2021.
APA	Xiao, Wei.,Jiao, Zhuo-Lei.,Senol, Esra.,Yao, Jiwei.,Zhao, Miao.,...&Xu, Xiao-Hong.(2021).Neural circuit control of innate behaviors.SCIENCE CHINA-LIFE SCIENCES.
MLA	Xiao, Wei,et al."Neural circuit control of innate behaviors".SCIENCE CHINA-LIFE SCIENCES (2021).