TT2 controls rice thermotolerance through SCT1-dependent alteration of wax biosynthesis

doi:10.1038/s41477-021-01039-0

	TT2 controls rice thermotolerance through SCT1-dependent alteration of wax biosynthesis
	Kan, Yi 1,2,3,4; Mu, Xiao-Rui 1,2,3; Zhang, Hai1,2,5 ; Gao, Jin 1,2,3; Shan, Jun-Xiang 1,2,4; Ye, Wang-Wei 1,2,4; Lin, Hong-Xuan1,2,3,4,5
	2022-01
发表期刊	NATURE PLANTS (IF:15.8[JCR-2023],17.1[5-Year])
ISSN	2055-026X
EISSN	2055-0278
发表状态	已发表
DOI	10.1038/s41477-021-01039-0
摘要	["TT2 is identified as a negative regulator of thermotolerance. It triggers Ca2+ signalling upon heat stress, which is then decoded by SCT1-CaM interaction. SCT1 reduces the transcription of its target OsWR2, thereby causing reduction in wax biosynthesis.","Global warming threatens crop production. G proteins mediate plant responses to multiple abiotic stresses. Here we identified a natural quantitative trait locus, TT2 (THEROMOTOLERANCE 2), encoding a G gamma subunit, that confers thermotolerance in rice during both vegetative and reproductive growth without a yield penalty. A natural allele with loss of TT2 function was associated with greater retention of wax at high temperatures and increased thermotolerance. Mechanistically, we found that a transcription factor, SCT1 (Sensing Ca2+ Transcription factor 1), functions to decode Ca2+ through Ca2+-enhanced interaction with calmodulin and acts as a negative regulator of its target genes (for example, Wax Synthesis Regulatory 2 (OsWR2)). The calmodulin-SCT1 interaction was attenuated by reduced heat-triggered Ca2+ caused by disrupted TT2, thus explaining the observed heat-induced changes in wax content. Beyond establishing a bridge linking G protein, Ca2+ sensing and wax metabolism, our study illustrates innovative approaches for developing potentially yield-penalty-free thermotolerant crop varieties."]
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收录类别	SCI ; SCIE
语种	英语
资助项目	National Natural Science Foundation of China[31788103,31630052] ; Chinese Academy of Sciences["XDB27010104","QYZDY-SSW-SMC023","159231KYSB20200008"] ; Laboratory of Lingnan Modern Agriculture Project[NT2021002]
WOS研究方向	Plant Sciences
WOS类目	Plant Sciences
WOS记录号	WOS:000739789100001
出版者	NATURE PORTFOLIO
引用统计	正在获取...
文献类型	期刊论文
条目标识符	https://kms.shanghaitech.edu.cn/handle/2MSLDSTB/148751
专题	生命科学与技术学院_博士生生命科学与技术学院_特聘教授组_林鸿宣组
通讯作者	Lin, Hong-Xuan
作者单位	1.Chinese Acad Sci, Shanghai Inst Plant Physiol & Ecol, CAS Ctr Excellence Mol Plant Sci, Natl Key Lab Plant Mol Genet, Shanghai, Peoples R China 2.Chinese Acad Sci, Shanghai Inst Plant Physiol & Ecol, Collaborat Innovat Ctr Genet & Dev, Shanghai, Peoples R China 3.Univ Chinese Acad Sci, Beijing, Peoples R China 4.Guangdong Lab Lingnan Modern Agr, Guangzhou, Peoples R China 5.ShanghaiTech Univ, Sch Life Sci & Technol, Shanghai, Peoples R China
通讯作者单位	生命科学与技术学院
推荐引用方式 GB/T 7714	Kan, Yi,Mu, Xiao-Rui,Zhang, Hai,et al. TT2 controls rice thermotolerance through SCT1-dependent alteration of wax biosynthesis[J]. NATURE PLANTS,2022.
APA	Kan, Yi.,Mu, Xiao-Rui.,Zhang, Hai.,Gao, Jin.,Shan, Jun-Xiang.,...&Lin, Hong-Xuan.(2022).TT2 controls rice thermotolerance through SCT1-dependent alteration of wax biosynthesis.NATURE PLANTS.
MLA	Kan, Yi,et al."TT2 controls rice thermotolerance through SCT1-dependent alteration of wax biosynthesis".NATURE PLANTS (2022).