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Axonal microRNAs: localization, function and regulatory mechanism during axon development | |
2017-04 | |
发表期刊 | JOURNAL OF MOLECULAR CELL BIOLOGY (IF:5.3[JCR-2023],6.1[5-Year]) |
ISSN | 1674-2788 |
卷号 | 9期号:2页码:82-90 |
发表状态 | 已发表 |
DOI | 10.1093/jmcb/mjw050 |
摘要 | Subcellular localization and translation of messenger RNAs are essential for the regulation of neuronal development and synaptic function. As post-transcriptional regulators, microRNAs (miRNAs) have been emerging as central players in the development and maturation of the nervous system. Recent discoveries reveal the critical functions of miRNAs in the axon of neurons via multiple pathways of molecular regulation. Here, we introduce methods for isolating axonal miRNAs and review recent findings on the localization and function as well as regulatory mechanism of axonal miRNAs during axon development. |
关键词 | axonal miRNA compartmentalized culture axon development RNA-binding protein |
收录类别 | SCI |
语种 | 英语 |
资助项目 | Shanghai Postdoctoral Science Foundation[12R21417300] |
WOS研究方向 | Cell Biology |
WOS类目 | Cell Biology |
WOS记录号 | WOS:000401759100002 |
出版者 | OXFORD UNIV PRESS |
WOS关键词 | LOCAL PROTEIN-SYNTHESIS ; MESSENGER-RNA LOCALIZATION ; SYMPATHETIC NEURONS ; GROWTH CONES ; OXIDATIVE-PHOSPHORYLATION ; CORTICAL-NEURONS ; DISTAL AXONS ; TRANSLATION ; TRANSPORT ; NERVE |
原始文献类型 | Review |
引用统计 | 正在获取...
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文献类型 | 期刊论文 |
条目标识符 | https://kms.shanghaitech.edu.cn/handle/2MSLDSTB/1431 |
专题 | 生命科学与技术学院_特聘教授组_鲍岚组 |
通讯作者 | Bao, Lan |
作者单位 | 1.Chinese Acad Sci, Shanghai Inst Biol Sci, Inst Biochem & Cell Biol, State Key Lab Cell Biol,CAS Ctr Excellence Mol Ce, Shanghai 200031, Peoples R China 2.ShanghaiTech Univ, Sch Life Sci & Technol, Shanghai 201210, Peoples R China |
通讯作者单位 | 生命科学与技术学院 |
推荐引用方式 GB/T 7714 | Wang, Bin,Bao, Lan. Axonal microRNAs: localization, function and regulatory mechanism during axon development[J]. JOURNAL OF MOLECULAR CELL BIOLOGY,2017,9(2):82-90. |
APA | Wang, Bin,&Bao, Lan.(2017).Axonal microRNAs: localization, function and regulatory mechanism during axon development.JOURNAL OF MOLECULAR CELL BIOLOGY,9(2),82-90. |
MLA | Wang, Bin,et al."Axonal microRNAs: localization, function and regulatory mechanism during axon development".JOURNAL OF MOLECULAR CELL BIOLOGY 9.2(2017):82-90. |
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