Concise Synthesis of Polycyclic Indoline Scaffolds through an In-III-Catalyzed Formal [4+2] Annulation of 2,3-Disubstituted Indoles with o-Aminobenzyl Alcohols

doi:10.1002/ejoc.201700432

	Concise Synthesis of Polycyclic Indoline Scaffolds through an In-III-Catalyzed Formal [4+2] Annulation of 2,3-Disubstituted Indoles with o-Aminobenzyl Alcohols
	Luo, Mupeng1,2 ; Chen, Jianxin1,2 ; Yu, Linqian 3; Wei, Wanguo1,2
	2017-05-10
发表期刊	EUROPEAN JOURNAL OF ORGANIC CHEMISTRY (IF:2.5[JCR-2023],2.6[5-Year])
ISSN	1434-193X
期号	18 页码:2652-2660
发表状态	已发表
DOI	10.1002/ejoc.201700432
摘要	A concise indium(III)-catalyzed annulation of 2,3-disubstituted indoles with o-aminobenzyl alcohols is reported. The in situ generated aza-ortho-quinone methides (aza-oQMs) were efficiently trapped by diverse carbazoles in a formal [4+2] cycloaddition reaction catalyzed by indium(III) triflate, which provided rapid access to bridged polycyclic indoline alkaloid skeletons.
关键词	Nitrogen heterocycles Fused-ring systems Cycloaddition Diastereoselectivity Indium
收录类别	SCI ; IC ; CCR
语种	英语
资助项目	Strategic Priority Research Program of the Chinese Academy of Sciences[XDA01040302]
WOS研究方向	Chemistry
WOS类目	Chemistry, Organic
WOS记录号	WOS:000401434900016
出版者	WILEY-V C H VERLAG GMBH
WOS关键词	ACTIVE CARBAZOLE ALKALOIDS ; N-(ORTHO-CHLOROMETHYL)ARYL AMIDES ; ENANTIOSELECTIVE SYNTHESIS ; ASYMMETRIC-SYNTHESIS ; QUINONE METHIDES ; SULFUR YLIDES ; COMMUNESIN F ; PEROPHORAMIDINE ; CYCLOADDITION ; CONSTRUCTION
原始文献类型	Article
引用统计	正在获取...
文献类型	期刊论文
条目标识符	https://kms.shanghaitech.edu.cn/handle/2MSLDSTB/1373
专题	生命科学与技术学院生命科学与技术学院_特聘教授组_魏万国组生命科学与技术学院_硕士生生命科学与技术学院_博士生
通讯作者	Wei, Wanguo
作者单位	1.Univ Chinese Acad Sci, Shanghai Adv Res Inst Chinese Acad Sci, Chinese Acad Sci, 99 Haike Rd, Shanghai 201210, Peoples R China 2.ShanghaiTech Univ, Sch Life Sci & Technol, 100 Haike Rd, Shanghai 201210, Peoples R China 3.Fudan Univ, Sch Pharmarcy, 826 Zhangheng Rd,Zhangjiang Hitech Pk, Shanghai 201203, Peoples R China
第一作者单位	生命科学与技术学院
通讯作者单位	生命科学与技术学院
推荐引用方式 GB/T 7714	Luo, Mupeng,Chen, Jianxin,Yu, Linqian,et al. Concise Synthesis of Polycyclic Indoline Scaffolds through an In-III-Catalyzed Formal [4+2] Annulation of 2,3-Disubstituted Indoles with o-Aminobenzyl Alcohols[J]. EUROPEAN JOURNAL OF ORGANIC CHEMISTRY,2017(18):2652-2660.
APA	Luo, Mupeng,Chen, Jianxin,Yu, Linqian,&Wei, Wanguo.(2017).Concise Synthesis of Polycyclic Indoline Scaffolds through an In-III-Catalyzed Formal [4+2] Annulation of 2,3-Disubstituted Indoles with o-Aminobenzyl Alcohols.EUROPEAN JOURNAL OF ORGANIC CHEMISTRY(18),2652-2660.
MLA	Luo, Mupeng,et al."Concise Synthesis of Polycyclic Indoline Scaffolds through an In-III-Catalyzed Formal [4+2] Annulation of 2,3-Disubstituted Indoles with o-Aminobenzyl Alcohols".EUROPEAN JOURNAL OF ORGANIC CHEMISTRY .18(2017):2652-2660.