Dynamic network biomarker analysis discovers IbNAC083 in the initiation and regulation of sweet potato root tuberization

doi:10.1111/tpj.15478

	Dynamic network biomarker analysis discovers IbNAC083 in the initiation and regulation of sweet potato root tuberization
	He, Shutao 1; Wang, Hongxia 2; Hao, Xiaomeng 2,3; Wu, Yinliang 2,3; Bian, Xiaofeng 2; Yin, Minhao 2,4; Zhang, Yandi 2,3; Fan, Weijuan 2; Dai, Hao 1; Yuan, Ling 5; Zhang, Peng 2,3; Chen, Luonan1,6,7
	2021-11
发表期刊	PLANT JOURNAL (IF:6.2[JCR-2023],7.1[5-Year])
ISSN	0960-7412
EISSN	1365-313X
卷号	108 期号:3 页码:793-813
DOI	10.1111/tpj.15478
摘要	The initiation and development of storage roots (SRs) are intricately regulated by a transcriptional regulatory network. One key challenge is to accurately pinpoint the tipping point during the transition from pre-swelling to SRs and to identify the core regulators governing such a critical transition. To solve this problem, we performed a dynamic network biomarker (DNB) analysis of transcriptomic dynamics during root development in Ipomoea batatas (sweet potato). First, our analysis identified stage-specific expression patterns for a significant proportion (>9%) of the sweet potato genes and unraveled the chronology of events that happen at the early and later stages of root development. Then, the results showed that different root developmental stages can be depicted by co-expressed modules of sweet potato genes. Moreover, we identified the key components and transcriptional regulatory network that determine root development. Furthermore, through DNB analysis an early stage, with a root diameter of 3.5 mm, was identified as the critical period of SR swelling initiation, which is consistent with morphological and metabolic changes. In particular, we identified a NAM/ATAF/CUC (NAC) domain transcription factor, IbNAC083, as a core regulator of this initiation in the DNB-associated network. Further analyses and experiments showed that IbNAC083, along with its associated differentially expressed genes, induced dysfunction of metabolism processes, including the biosynthesis of lignin, flavonol and starch, thus leading to the transition to swelling roots.
关键词	Ipomoea batatas storage root development transcriptome dynamics co-expression network dynamic network biomarker tipping point IbNAC083
收录类别	SCIE ; EI
语种	英语
WOS研究方向	Plant Sciences
WOS类目	Plant Sciences
WOS记录号	WOS:000697261900001
出版者	WILEY
原始文献类型	Article; Early Access
引用统计	正在获取...
文献类型	期刊论文
条目标识符	https://kms.shanghaitech.edu.cn/handle/2MSLDSTB/128223
专题	生命科学与技术学院_特聘教授组_陈洛南组
通讯作者	Zhang, Peng; Chen, Luonan
作者单位	1.Chinese Acad Sci, Shanghai Inst Biochem & Cell Biol, CAS Ctr Excellence Mol Cell Sci, State Key Lab Cell Biol, Shanghai 200031, Peoples R China; 2.Chinese Acad Sci, Inst Plant Physiol & Ecol, CAS Ctr Excellence Mol Plant Sci, Natl Key Lab Plant Mol Genet, Shanghai 200032, Peoples R China; 3.Univ Chinese Acad Sci, CAS Ctr Excellence Mol Plant Sci, Beijing 100049, Peoples R China; 4.Henan Univ Sci & Technol, Coll Tree Peony, Luoyang 471000, Peoples R China; 5.Univ Kentucky, Dept Plant & Soil Sci, Lexington, KY 40506 USA; 6.Univ Chinese Acad Sci, Chinese Acad Sci, Hangzhou Inst Adv Study, Key Lab Syst Hlth Sci Zhejiang Prov, Hangzhou 310024, Peoples R China; 7.ShanghaiTech Univ, Sch Life Sci & Technol, Shanghai 201210, Peoples R China
通讯作者单位	生命科学与技术学院
推荐引用方式 GB/T 7714	He, Shutao,Wang, Hongxia,Hao, Xiaomeng,et al. Dynamic network biomarker analysis discovers IbNAC083 in the initiation and regulation of sweet potato root tuberization[J]. PLANT JOURNAL,2021,108(3):793-813.
APA	He, Shutao.,Wang, Hongxia.,Hao, Xiaomeng.,Wu, Yinliang.,Bian, Xiaofeng.,...&Chen, Luonan.(2021).Dynamic network biomarker analysis discovers IbNAC083 in the initiation and regulation of sweet potato root tuberization.PLANT JOURNAL,108(3),793-813.
MLA	He, Shutao,et al."Dynamic network biomarker analysis discovers IbNAC083 in the initiation and regulation of sweet potato root tuberization".PLANT JOURNAL 108.3(2021):793-813.