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Generation of a human induced pluripotent stem cell line (SIAISi010-A) from a 31-year-old healthy donor with Chinese Han genetic background | |
2021-05 | |
发表期刊 | STEM CELL RESEARCH (IF:0.8[JCR-2023],1.1[5-Year]) |
ISSN | 1873-5061 |
卷号 | 53 |
发表状态 | 已发表 |
DOI | 10.1016/j.scr.2021.102314 |
摘要 | A healthy 31-year-old Chinese Han female donated peripheral blood mononuclear cells (PBMC). Her PBMCs were reprogrammed with human OKSM (OCT3/4, KLF4 SOX2, and c-MYC) transcription factors by the non-integrating episomal vector system. Immunocytochemistry for pluripotency markers confirmed the pluripotency of transgene-free iPSCs. Their ability to differentiate spontaneously three germ layers in vitro is also confirmed. The iPSC line displayed a normal karyotype. This model can be used as a control in pathological mechanism studies. |
URL | 查看原文 |
收录类别 | SCI ; SCIE |
语种 | 英语 |
WOS研究方向 | Cell Biology ; Biotechnology & Applied Microbiology |
WOS类目 | Cell & Tissue Engineering ; Biotechnology & Applied Microbiology ; Cell Biology |
WOS记录号 | WOS:000663438300009 |
出版者 | ELSEVIER |
原始文献类型 | Article |
引用统计 | 正在获取...
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文献类型 | 期刊论文 |
条目标识符 | https://kms.shanghaitech.edu.cn/handle/2MSLDSTB/126982 |
专题 | 生命科学与技术学院_硕士生 |
共同第一作者 | Di,Weihao; Zhang,Bei |
推荐引用方式 GB/T 7714 | Dai,Qiuting,Di,Weihao,Zhang,Yi,et al. Generation of a human induced pluripotent stem cell line (SIAISi010-A) from a 31-year-old healthy donor with Chinese Han genetic background[J]. STEM CELL RESEARCH,2021,53. |
APA | Dai,Qiuting.,Di,Weihao.,Zhang,Yi.,Gu,Shixin.,Zhao,Jian.,...&Wang,Ying.(2021).Generation of a human induced pluripotent stem cell line (SIAISi010-A) from a 31-year-old healthy donor with Chinese Han genetic background.STEM CELL RESEARCH,53. |
MLA | Dai,Qiuting,et al."Generation of a human induced pluripotent stem cell line (SIAISi010-A) from a 31-year-old healthy donor with Chinese Han genetic background".STEM CELL RESEARCH 53(2021). |
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