AdmixSim: A Forward-Time Simulator for Various Complex Scenarios of Population Admixture

doi:10.3389/fgene.2020.601439

	AdmixSim: A Forward-Time Simulator for Various Complex Scenarios of Population Admixture
	Yang, Xiong 1,2; Yuan, Kai 1,2; Ni, Xumin 3; Zhou, Ying 1,2; Guo, Wei 4; Xu, Shuhua1,2,5,6,7,8
	2020-12-03
发表期刊	FRONTIERS IN GENETICS (IF:2.8[JCR-2023],3.3[5-Year])
卷号	11
发表状态	已发表
DOI	10.3389/fgene.2020.601439
摘要	Background: Population admixture is a common phenomenon in humans, animals, and plants, and it plays a very important role in shaping individual genetic architecture and population genetic diversity. Inference of population admixture, however, is very challenging and typically relies on in silico simulation. We are aware of the lack of a computerized tool for such a purpose. A simulator capable of generating data under various complex admixture scenarios would facilitate the study of recombination, linkage disequilibrium, ancestry tracing, and admixture dynamics in admixed populations. We described such a simulator here.
关键词	simulation population admixture genetic ancestry Wright Fisher model admixture model
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收录类别	SCI ; SCIE
语种	英语
资助项目	National Science Fund for Distinguished Young Scholars[31525014] ; National Natural Science Foundation of China (NSFC)[32030020][91731303][31771388][31961130380][31900418][32041008][11801027] ; Chinese Academy of Sciences (CAS)[XDB38000000][QYZDJ-SSW-SYS009] ; UK Royal Society-Newton Advanced Fellowship[NAF\R1\191094] ; National Key Research and Development Program[2016YFC0906403] ; Shanghai Municipal Science and Technology Major Project[2017SHZDZX01] ; Fundamental Research Funds for the Central Universities[2020RC001]
WOS研究方向	Genetics & Heredity
WOS类目	Genetics & Heredity
WOS记录号	WOS:000599279200001
出版者	FRONTIERS MEDIA SA
引用统计	正在获取...
文献类型	期刊论文
条目标识符	https://kms.shanghaitech.edu.cn/handle/2MSLDSTB/124920
专题	生命科学与技术学院_特聘教授组_徐书华组
通讯作者	Xu, Shuhua
作者单位	1.Chinese Acad Sci, Key Lab Computat Biol, Shanghai, Peoples R China 2.Chinese Acad Sci, Univ Chinese Acad Sci, Shanghai Inst Nutr & Hlth, Max Planck Soc MPG,Partner Inst Computat Biol, Shanghai, Peoples R China 3.Beijing Jiaotong Univ, Sch Sci, Dept Math, Beijing, Peoples R China 4.Chinese Acad Sci, Acad Math & Syst Sci, Inst Appl Math, Beijing, Peoples R China 5.ShanghaiTech Univ, Sch Life Sci & Technol, Shanghai, Peoples R China 6.Chinese Acad Sci, Ctr Excellence Anim Evolut & Genet, Kunming, Yunnan, Peoples R China 7.Zhengzhou Univ, Henan Inst Med & Pharmaceut Sci, Zhengzhou, Peoples R China 8.Fudan Univ, Collaborat Innovat Ctr Genet & Dev, Shanghai, Peoples R China
通讯作者单位	生命科学与技术学院
推荐引用方式 GB/T 7714	Yang, Xiong,Yuan, Kai,Ni, Xumin,et al. AdmixSim: A Forward-Time Simulator for Various Complex Scenarios of Population Admixture[J]. FRONTIERS IN GENETICS,2020,11.
APA	Yang, Xiong,Yuan, Kai,Ni, Xumin,Zhou, Ying,Guo, Wei,&Xu, Shuhua.(2020).AdmixSim: A Forward-Time Simulator for Various Complex Scenarios of Population Admixture.FRONTIERS IN GENETICS,11.
MLA	Yang, Xiong,et al."AdmixSim: A Forward-Time Simulator for Various Complex Scenarios of Population Admixture".FRONTIERS IN GENETICS 11(2020).