ShanghaiTech University Knowledge Management System
Decision tree searching strategy to boost the identification of cross-linked peptides. | |
2020-10-20 | |
发表期刊 | ANALYTICAL CHEMISTRY |
ISSN | 0003-2700 |
EISSN | 1520-6882 |
卷号 | 92期号:20页码:13702-13710 |
发表状态 | 已发表 |
DOI | 10.1021/acs.analchem.0c00452 |
摘要 | We describe an efficient decision tree searching strategy (DTSS) to boost the identification of cross-linked peptides. The DTSS approach allows the identification of a wealth of complementary information to facilitate the construction of more protein-protein interaction networks for human cell lysate, which was tested by the use of a recently reported cross-linking data set (ACS Cent. Sci. 2019, 5, 1514-1522). A variant of the PhoX-linker, named pDSPE, was synthesized and applied to cross-link Escherichia coli cell lysate to demonstrate that the acquisition of doubly charged ions can significantly improve identification results. The method can be seamlessly integrated to other search engines to maximize the number of identified cross-links. |
学科门类 | 理学::化学 |
URL | 查看原文 |
收录类别 | SCI ; SCIE ; EI |
WOS研究方向 | Chemistry |
WOS类目 | Chemistry, Analytical |
WOS记录号 | WOS:000584418100017 |
出版者 | AMER CHEMICAL SOC |
引用统计 | |
文献类型 | 期刊论文 |
条目标识符 | https://kms.shanghaitech.edu.cn/handle/2MSLDSTB/123629 |
专题 | 生命科学与技术学院_硕士生 免疫化学研究所_特聘教授组_抗体化学实验室 免疫化学研究所_公共科研平台_分析化学平台 物质科学与技术学院_博士生 |
共同第一作者 | Gao, Xiuxia |
通讯作者 | Jiang, Biao; Chen, Hongli; Chen, Wenzhang |
作者单位 | 1.ShanghaiTech Univ, Shanghai Inst Adv Immunochem Studies, Shanghai 201210, Peoples R China 2.Univ Chinese Acad Sci, Beijing 100049, Peoples R China |
第一作者单位 | 免疫化学研究所 |
通讯作者单位 | 免疫化学研究所 |
第一作者的第一单位 | 免疫化学研究所 |
推荐引用方式 GB/T 7714 | Huang, Rong,Gao, Xiuxia,Xu, Zili,et al. Decision tree searching strategy to boost the identification of cross-linked peptides.[J]. ANALYTICAL CHEMISTRY,2020,92(20):13702-13710. |
APA | Huang, Rong.,Gao, Xiuxia.,Xu, Zili.,Zhu, Wei.,Wei, Ding.,...&Chen, Wenzhang.(2020).Decision tree searching strategy to boost the identification of cross-linked peptides..ANALYTICAL CHEMISTRY,92(20),13702-13710. |
MLA | Huang, Rong,et al."Decision tree searching strategy to boost the identification of cross-linked peptides.".ANALYTICAL CHEMISTRY 92.20(2020):13702-13710. |
条目包含的文件 | ||||||
文件名称/大小 | 文献类型 | 版本类型 | 开放类型 | 使用许可 |
修改评论
除非特别说明,本系统中所有内容都受版权保护,并保留所有权利。