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Visible Light-Responsive Hydrogels for Cellular Dynamics: A Dual Mechanism Approach to Spatiotemporal Viscoelastic Regulation 期刊论文
NATURE COMMUNICATIONS, 2024
作者:  Yan Lu;  Yijun Zheng;  Dongshi Guan;  Cheng Chen;  Hangyu Li
收藏  |  浏览/下载:27/0  |  提交时间:2024/11/05
Discovery of Trametinib as an orchestrator for cytoskeletal vimentin remodeling 期刊论文
JOURNAL OF MOLECULAR CELL BIOLOGY, 2024, 卷号: 16, 期号: 3
作者:  Zhao, Shuangshuang;  Li, Zhifang;  Zhang, Qian;  Zhang, Yue;  Zhang, Jiali
Adobe PDF(3271Kb)  |  收藏  |  浏览/下载:67/4  |  提交时间:2024/09/23
PINX1 loss confers susceptibility to PARP inhibition in pan-cancer cells 期刊论文
CELL DEATH & DISEASE, 2024, 卷号: 15, 期号: 8
作者:  Huang, Mei;  Zhu, Xiaotong;  Wang, Chen;  He, Liying;  Li, Lei
Adobe PDF(5073Kb)  |  收藏  |  浏览/下载:201/46  |  提交时间:2024/09/02
Legionella effector LnaB is a phosphoryl-AMPylase that impairs phosphosignalling 期刊论文
NATURE, 2024, 卷号: 631, 期号: 8020
作者:  Wang, Ting;  Song, Xiaonan;  Tan, Jiaxing;  Xian, Wei;  Zhou, Xingtong
Adobe PDF(14913Kb)  |  收藏  |  浏览/下载:88/3  |  提交时间:2024/08/14
NAMPT-targeting PROTAC and nicotinic acid co-administration elicit safe and robust anti-tumor efficacy in NAPRT-deficient pan-cancers 期刊论文
CELL CHEMICAL BIOLOGY, 2024, 卷号: 31, 期号: 6
作者:  Zhu, Xiaotong;  Li, Ye;  Liu, Haixia;  Wang, Yuetong;  Sun, Renhong
Adobe PDF(7503Kb)  |  收藏  |  浏览/下载:188/16  |  提交时间:2024/07/15
THEMIS is a substrate and allosteric activator of SHP1, playing dual roles during T cell development 期刊论文
NATURE STRUCTURAL & MOLECULAR BIOLOGY, 2024, 卷号: 31, 期号: 1
作者:  Zhang, Jiali;  Jiang, Zhenzhou;  Zhang, Xueyuan;  Yang, Ziqun;  Wang, Jinjiao
Adobe PDF(6453Kb)  |  收藏  |  浏览/下载:545/2  |  提交时间:2023/09/22
Development of the nonreceptor tyrosine kinase FER-targeting PROTACs as a potential strategy for antagonizing ovarian cancer cell motility and invasiveness 期刊论文
JOURNAL OF BIOLOGICAL CHEMISTRY, 2023, 卷号: 299, 期号: 6
作者:  Zhang, Yanchun;  Xiong, Xuexue;  Sun, Renhong;  Zhu, Xiaotong;  Wang, Chen
Adobe PDF(2978Kb)  |  收藏  |  浏览/下载:143/5  |  提交时间:2024/04/12
Development of the non-receptor tyrosine kinase FER-targeting PROTACs as a potential strategy for antagonizing ovarian cancer cell motility and invasiveness 期刊论文
JOURNAL OF BIOLOGICAL CHEMISTRY, 2023
作者:  Yanchun Zhang;  Xuexue Xiong;  Renhong Sun;  Xiaotong Zhu;  Chen Wang
Adobe PDF(2707Kb)  |  收藏  |  浏览/下载:183/4  |  提交时间:2023/09/25
基于NAMPT靶蛋白的蛋白降解复合物及其应用 专利
申请号:WOCN22114935,申请日期: 2023-03-09,类型:发明申请,状态:未进入国家阶段-PCT有效期满
发明人:  Yang Xiaobao;  Fan Gaofeng;  Jiang Biao;  Liu Haixia;  Zhu Xiaotong
Adobe PDF(23700Kb)  |  收藏  |  浏览/下载:158/2  |  提交时间:2023/04/25
基于NAMPT靶蛋白的蛋白降解化合物及其应用 专利
申请号:CN202211025050.6,申请日期: 2023-03-07,类型:发明申请,状态:实质审查
发明人:  杨小宝;  范高峰;  姜标;  刘海霞;  朱小童
Unknown(29165Kb)  |  收藏  |  浏览/下载:301/1  |  提交时间:2023/03/07